RT  - Journal of Clinical Pediatric Dentistry
ID  - 10.17796/1053-4625-45.5.6
T1  - A Comparative Quantitative Assessment of Salivary Iga and Alpha Amylase in Caries Free and Caries Active Children
A1  - Asib Ahmad
A1  - Dipanshu Kumar
A1  - Aparna Singh
A1  - Siddharth Anand
A1  - Nidhi Agarwal
A1  - Riyaz Ahmad
K1  - Dental caries; Unstimulated whole saliva; Enzyme linked immunosorbent assay; Salivary IgA; Amylase
YR  - 2021
SP  - 323
AB  - <p><strong>Objectives:</strong> The aim of the study was to assess the salivary IgA (immunoglobulin A) and alpha amylase levels in the unstimulated whole saliva samples of caries-free and caries-active children and correlate it with the caries status and age. <strong>Study design:</strong> The salivary IgA and amylase was investigated in 100 children in the range of 8–12 years divided in two groups, control group (DMFT and/or deft = 0) and study group (DMFT/deft score ≥5). The salivary IgA was measured using kit based on two-site sandwich enzyme immunoassay principle and amylase was estimated using the vitro amyl slides. <strong>Results</strong> :The mean salivary IgA and amylase levels in the saliva of the children in the control group was found to be significantly increased (p=.001 and p=.014 respectively) whereas the relationship between salivary IgA and amylase levels in the saliva of the children was found to be insignificant with the age (p=.392 and p=.306 respectively). <strong>Conclusions:</strong> The results indicated that salivary IgA and amylase levels in saliva increased significantly in caries free children and the level of salivary IgA and alpha amylase has no significant relation with the age of the children.</p>