RT  - Journal of Clinical Pediatric Dentistry
ID  - 10.17796/1053-4625-45.6.10
T1  - Safety and Efficacy of IV Dexmedetomidine as an Adjunct to Propofol to Sedate Anxious and Uncooperative Pediatric Dental Patients: A Randomized Controlled Trial
A1  - Ferah Rehman
A1  - Ashima Goyal
A1  - Krishan Gauba
A1  - Kajal Jain
A1  - Aditi Kapur
K1  - Dexmedetomidine; Deep sedation; Analgesia; Propofol; Outpatient; Pediatric dentistry
YR  - 2021
SP  - 428
AB  - <p>Objective: To evaluate the safety and efficacy of dexmedetomidine (dex) as an adjunct to propofol sedation in pediatric dental patients. Study design: This RCT enrolled 30 anxious ASA-I 2-5 year olds. Allocated into 2 groups either receiving IV propofol (1 mg/kg)(Gp-P) or [IV dex (1ug/kg) with propofol(1 mg/kg)] (Gp-D) after oral midazolam premedication (0.5 mg/kg). Sedation maintained with propofol infusion at 50–75ug/kg/min. Additional bolus/es of propofol (1mg/kg) was/were administered in case of inadequate sedation. Primary outcome was to compare requirement of propofol in two groups. Secondary outcomes were to compare vital signs, depth of sedation, induction, treatment and recovery time, intra &amp; post-operative complications and analgesic requirement post-operatively.</p>