RT  - Journal of Clinical Pediatric Dentistry
ID  - 10.17796/1053-4628-42.3.11
T1  - Dental Caries in Children and Adolescents During and After Antineoplastic Chemotherapy
A1  - Dorota Olczak-Kowalczyk
A1  - Ewa Krasuska-Sławińska
A1  - Agnieszka Brożyna
A1  - Anna Turska-Szybka
A1  - Bożenna Dembowska-Bagińska
K1  - neoplasm
K1  - chemotherapy
K1  - children
K1  - dental caries
YR  - 2018
SP  - 225
AB  - <p><strong>Objective:</strong> To assess caries incidence, intensity, and treatment in children and adolescents under/after antineoplastic treatment. <strong>Study design:</strong> Patients with permanent and mixed dentition were divided into three groups of 60 patients each (5–18 years): CH <strong>–</strong> under chemotherapy; PCH – after chemotherapy; CG – generally healthy subjects. Caries incidence, intensity (DMFT/dmft, DMFS/dmfs), and mean numbers of teeth/surfaces with white spot lesions–WSL (D<sub>1+2</sub>/d<sub>1+2</sub>) were assessed following the ICDAS-II criteria. Statistical analysis: Mann-Whitney U test, significance at p≤0.05). <strong>Results:</strong> Caries incidence was significantly higher in PCH and CH <strong>(</strong>88.33% and 90%) than in CG (66.66%). Caries intensity was higher in both mixed and permanent dentition in patients under and after chemotherapy. The DMFS/DMFT correlation was the highest in PCH. Treatment indexes for primary and permanent teeth treatment were significantly lower in PCH and CH than CG. <strong>Conclusion</strong>: Antineoplastic chemotherapy is associated with caries development and its high incidence during/after treatment. As dental hygiene was poor in patients under and after antineoplastic treatment, dental checkups need to be more frequent and thorough.</p>