Article Data

  • Views 769
  • Dowloads 188

Original Research

Open Access

Titanium Dioxide Nanoparticles and Cetylpyridinium Chloride Enriched Glass Ionomer Restorative Cement: A Comparative Study Assessing Compressive Strength and Antibacterial Activity

  • Nida Hamid1
  • Ravishankar Lingesha Telgi1,*,
  • Amit Tirth1
  • Vaibhav Tandon1
  • Smita Chandra1
  • Rupesh Kumar Chaturvedi2

1Department of Public Health Dentistry, Kothiwal Dental College and Research Centre, Uttar Pradesh, India

2Department of Oral Pathology and Microbiology, Kothiwal Dental College and Research Centre, Uttar Pradesh, India

DOI: 10.17796/1053-4625-43.1.8 Vol.43,Issue 1,January 2019 pp.42-45

Published: 01 January 2019

*Corresponding Author(s): Ravishankar Lingesha Telgi E-mail: telgiravi@yahoo.com

Abstract

Objective: To evaluate the addition of titanium dioxide (TiO2) nanoparticles and cetylpyridinium chloride (CPC) on the compressive strength and antibacterial activity of conventional glass-ionomer cement (GIC). Study design: TiO2 nanoparticles enriched GIC was prepared by adding 3% TiO2 nanoparticles (w/w) into the powder component of conventional GIC. CPC containing GIC was developed by incorporating 1% CPC (w/w) into conventional GIC powder. Samples were segregated into three groups: GIC with 3% TiO2 nanoparticles, GIC with 1% CPC and unmodified conventional GIC. Compressive strength was assessed using the universal testing machine on cylindrical specimens made from each material. Antibacterial activity was assessed by measuring inhibition zones on Mitis Salivarius Bacitracin (MSB) agar inoculated with pure strain of Streptococcus mutans (S. mutans). Results: GIC containing TiO2 nanoparticles exhibited significantly greater compressive strength as compared with CPC and conventional GIC groups (P < 0.01). However, there was no significant difference between the compressive strengths of CPC and conventional GIC group (P >0.05). Antibacterial activity was significantly greater for TiO2 group than conventional GIC (P <0.05). CPC increased the antibacterial activity of conventional GIC, though not significantly. Conclusion: The addition of 3% TiO2 nanoparticles improves the compressive strength of GIC as well as its antibacterial activity against S. mutans.

Keywords

Glass ionomer; TiO2; Nanoparticles; Cetylpyridinium chloride; CPC; Compressive strength; Antibacterial activity

Cite and Share

Nida Hamid,Ravishankar Lingesha Telgi,Amit Tirth,Vaibhav Tandon,Smita Chandra,Rupesh Kumar Chaturvedi. Titanium Dioxide Nanoparticles and Cetylpyridinium Chloride Enriched Glass Ionomer Restorative Cement: A Comparative Study Assessing Compressive Strength and Antibacterial Activity. Journal of Clinical Pediatric Dentistry. 2019. 43(1);42-45.

References

1. Elsaka SE, Hamouda IM, Swain MV. Titanium dioxide nanoparticles addition to a conventional glass-ionomer restorative: Influence on physical and antibacterial properties. J Dent 39(9): 589-598, 2011.

2. El-Negoly SA, El-Fallal AA, El-Sherbiny IM. A new modification for improving shear bond strength and other mechanical properties of conventional glass-ionomer restorative materials. J Adhes Dent 16: 41- 47, 2014.

3. Dimkov A, Nicholson WJ, Gjorgievska E, Booth S. Compressive strength and setting time determination of glass-ionomer cements incorporated with cetylpyridinium chloride and benzalkonium chloride. Prilozi 33(1): 243- 63, 2012.

4. Prabhakar AR, Sonali Agarwal, Basappa N. Comparative evaluation of antibacterial effect and physical properties of conventional glass-ionomer cement containing 1% chlorhexidine and 1% xylitol. International Journal of Oral Health Sciences 4: 63-69, 2014.

5. Takahashi Y, Imazato S, Kaneshiro AV, Ebisu S, Frencken JE, Tay FR. Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexidine for the ART approach. Dental Materials 22: 647- 652, 2006.

6. Yesilyurt C, Er K, Tasdemir T, Buruk K, Celik D. Antibacterial activity and physical properties of glass-ionomer cements containing antibiotics. Operative Dentistry 34-1: 18-23, 2009.

7. Lee VA, Karthikeyan R, Rawls HR, Amaechi BT. Anti-cariogenic effect of a cetylpyridinium chloride containing nanoemulsion. Journal of Dentistry 38: 742-749, 2010.

8. Versteeg PA, Rosema NAM, Hoenderdos NL, Slot DE, Van der Weijden GA. The plaque inhibitory effect of a CPC mouthrinse in a 3-day plaque accumulation model – a cross-over study. Int J Dent Hygiene 8(4): 269- 75, 2010.

9. Phan TN, Buckner T, Sheng J, Baldeck JD, Marquis RE. Physiologic actions of zinc related to inhibition of acid and alkali production by oral streptococci in suspensions and biofilms. Oral Microbiol Immunol 19: 31- 8, 2004.

10. Lansdown AB. Silver in health care: Antimicrobial effects and safety in use. Curr Probl Dermatol 33: 17-34, 2006.

11. Morones JR, Elechiguerra JL, Camacho A, Holt K, Kouri JB, Ramírez JT, et al. The bactericidal effect of silver nanoparticles. Nanotechnology 16: 2346-53, 2005.

12. Aydin Sevinç B, Hanley L. Antibacterial activity of dental composites containing zinc oxide nanoparticles. J Biomed Mater Res B Appl Biomater 94: 22-31, 2010.

13. Heravi F, Ramezani M, Poosti M, Hosseini M, Shajiei A, Ahrari F. In vitro cytotoxicity assessment of an orthodontic composite containing titanium-dioxide nanoparticles. J Dent Res Dent Clin Dent Prospects 7: 192- 8, 2013.

14. Sadeghi R, Olia P, Rezvani MB, Taleghani F, Sharif F. Comparison of the nanosilver and chlorhexidin antimicrobial effect on Streptococcus sangius and actinomicosis viscosus. J Islamic Dent Assoc 23: 225-31, 2010.

15. Besinis A, De Peralta T, Handy RD. The antibacterial effects of silver, titanium dioxide and silica dioxide nanoparticles compared to the dental disinfectant chlorhexidine on Streptococcus mutans using a suite of bioassays. Nanotoxicology. 8(1): 1-16, Feb 2014.

16. Yang J, Mei S, Ferreira JMF. Hydrothermal synthesis of nanosized titania powders: influence of tetraalkyl ammonium hydroxides on particle characteristics. Journal of the American Ceramic Society 84: 1696-702, 2001.

17. Zhang R, Gao L. Effect of peptization on phase transformation of TiO2 nanoparticles. Materials Research Bulletin 36: 1957-65, 2001.

18. ISO. ISO 9917-1: dentistry-water-based cements—part 1: powder/liquid acid–base cements. Geneva, Switzerland: International Organization for Standardization; 2007.

19. Al Zraikat H, Palamara JE, Messer HH, Burrow MF, Reynolds EC. The incorporation of casein phosphopeptide-amorphous calcium phosphate into a glass-ionomer cement. Dental Materials 27:235-43, 2011.

20. Wilson AD, Kent BE. A new translucent cement for dentistry. The glass-ionomer cement. British Dental Journal 132: 133-5, 1972.

21. Anusavice KJ, Phillips RW. Phillips’ science of dental materials. 11th ed. St. Louis, MO: Saunders; 2003.

22. Powers JM, Sakaguchi RL. Craig’s restorative dental materials. 12th ed. St. Louis, MO: Mosby Elsevier; 2006.

23. Pinheiro SL, Simionato MR, Imparato JC, Oda M. Antibacterial activity of glass-ionomer cement containing antibiotics on caries lesion microorganisms. American Journal of Dentistry 18: 261-6, 2005.

24. Pitten FA, Kramer A. Efficacy of Cetylpyridinium Chloride Used as Oropharyngeal Antiseptic. Arzneim.-Forsch./Drug Res 51(7): 588-95, 2001.

25. Jesline A, John NP, Narayanan P M, Vani C, Murugan S. Antimicrobial activity of zinc and titanium dioxide nanoparticles against biofilm-producing methicillin-resistant Staphylococcus aureus. Appl Nanosci 5: 157- 162, 2015.

26. Wetzel B, Rosso P, Haupert F, Friedrich K. Epoxy nanocomposites—fracture and toughening mechanisms. Engineering Fracture Mechanics 73: 2375–98, 2006.

27. Xia Y, Zhang F, Xie H, Gu N. Nanoparticle-reinforced resin-based dental composites. Journal of Dentistry 36: 450-5, 2008.

28. Thomas A, Raj MS, Venkataramana J. Antimicrobial activity of tio2 nanoparticles against microbial isolates causing dental plaques. Int J Bioassays 3(06): 3106-3110, 2014.

29. Garcia-Contreras R, Scougall-Vilchis RJ, Contreras-Bulnes R, Sakagami H, Morales-Luckie RA, Nakajima H. Mechanical, antibacterial and bond strength properties of nano-titanium-enriched glass-ionomer cement. J Appl Oral Sci. 23(3): 321-8, May-Jun 2015.

30. Ahrari F, Eslami N, Rajabi O, Ghazvini K, Barati S. The antimicrobial sensitivity of Streptococcus mutans and Streptococcus sangius to colloidal solutions of different nanoparticles applied as mouthwashes. Dent Res J (Isfahan). 12(1): 44-9, Jan-Feb 2015.

31. Denyer SP, Stewart GSAB. Mechanisms of action of disinfectants. International Biodeterioration and Biodegradation 41: 261-8, 1998.

32. Steinberg D, Bachrach G, Gedalia I, Abu-Ata S, Rozen R. Effects of various antiplaque agents on fructosyltransferase activity in solution and immobilized onto hydroxyapatite. European Journal of Oral Sciences 110: 374–9, 2002.

33. Loyola-Rodriguez JP, Garcia-Godoy F, Lindquist R. Growth inhibition of glass-ionomer cements on mutans streptococci. Pediatr Dent. 16(5): 346-9, Sep-Oct 1994.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

PubMed (MEDLINE) PubMed comprises more than 35 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 2.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time

Conferences

Top