Remineralizing Potential of Clinpro® and Tooth Mousse Plus® on Artificial Carious Lesions

Background: Calcium phosphate and fluoride (F) delivery systems claim to facilitate enamel remineralization. Aim: To evaluate and compare (i) the remineralizing potential of Clinpro^® Tooth Crème(CTC) and Tooth Mousse Plus^®(TMP) on artificial carious lesions, and (ii) the benefit of 1000ppm F dentifrice prior to the application of CTC and TMP. Study design: Carious lesions, 200–300μm deep were produced by placing molars in demineralizing solution for 96h, sections 100–150μm thick were then randomly assigned to six groups(n=150). Specimens were treated thrice daily with a non-fluoridated(Group A), or fluoridated dentifrice[1000ppm, (Group B)], or CTC(Group C), TMP(Group D), fluoridated dentifrice followed by CTC(Group E), or a fluoridated dentifrice followed by TMP(Group F), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography. Results: Posttreatment maximum mineral content at the surface zone(V_max) was significantly increased in Groups B, C, and D compared to the other groups. The lesion depth(LD) decreased in Group D>Group C>Group E, and the net mineral content gain(ΔZ) in Group C>Group D, which did not reach statistical significance. Conclusions: CTC and TMP exhibited similar efficacy in remineralizing artificial carious lesions. Nevertheless, the net mineral gain or lesion consolidation following CTC use was higher than TMP.

Remineralization; Tooth mousse plus, Clinpro

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