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Case Reports
Open AccessGingival Plasma Cell Granuloma: A case Report of Multiple Lesions
Gingival Plasma Cell Granuloma: A case Report of Multiple Lesions
1Department of periodontology, Affiliated Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
2Department of Oral Implantology and Prosthodontics, Affiliated Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
3Department of Pathology, Second Affiliated hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China
*Corresponding Author(s): Fu-ming He E-mail: hfm@zju.edu.cn.
Abstract
Background: Plasma cell granuloma (PCG) is a rare benign pseudotumorous proliferation of unclear etiology that is mainly situated in the lungs. Gingival PCG is an even more peculiar lesion that usually occurs in middle-aged or elderly individuals and clinically manifests as a solitary entity. Case report: A 15-year-old male with no underlying medical conditions presented with multiple gingival masses in the right maxilla, which were initially thought to be epulis. The lesions were resected completely and the excisional biopsies sent for histological examination. Immunohistochemical (IHC) stain revealed dense polyclonal plasma cell infiltration with positive expression of both kappa and lambda light chains, confirming a diagnosis of gingival PCG. Subsequently, the affected gingiva healed uneventfully, with no sign of recurrence over 2 years of follow-up. Conclusions: The present report depicts an extremely unusual case of gingival PCG occurring in a juvenile with multiple lesions, which is worth attention in clinical pediatric dentistry. Excisional-biopsy and histological investigations are imperative for a confirmative diagnosis and to exclude potential aggressive conditions. Complete resection of lesions seems to be a valid treatment, while long-term clinical follow-up is still needed.
Keywords
Plasma cell granuloma; Excisional biopsy; Histological analysis; Immunohistochemical staining
Cite and Share
Wei Lu,Gang-gang Qi,Xiao-jun Li,Fu-ming He,Bo Hong. Gingival Plasma Cell Granuloma: A case Report of Multiple Lesions. Journal of Clinical Pediatric Dentistry. 2020. 44(6);436-441.
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