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Open AccessEvaluation of Serum 25(OH)D Levels in Obese and Normal-Weight Children with Carious and Hypomineralized Teeth
Evaluation of Serum 25(OH)D Levels in Obese and Normal-Weight Children with Carious and Hypomineralized Teeth
1Bezmialem Vakif University, Faculty of Dentistry, Department of Pediatric Dentistry, İstanbul, Turkey
2Aydin Adnan Menderes University, Faculty of Dentistry, Department of Pediatric Dentistry, Aydin, Turkey
3Aydin Adnan Menderes University, Faculty of Medicine, Department of Pediatric Endocrinology, Aydin, Turkey
*Corresponding Author(s): Gülçin Doğusal E-mail: gdogusal@gmail.com
Abstract
Aim: The aim of this study was to assess the association between dental caries, molar incisor hypomineralisation (MIH) and obesity in relationship with different vitamin D levels in children. Study design: This retrospective case-controlled study enrolled 455 children aged 6–18 years, who attended to both pediatric endocrinology and pediatric dentistry clinics at the Aydin Adnan Menderes University Hospital, Turkey. Vitamin D status was measured with serum (25(OH)D) concentrations. Body mass index (BMI) were used to determine adiposity. Caries status was assessed using the decayed-missing-filled teeth (dft) and (DMFT) index for primary and permanent dentitions using WHO standard methodology. MIH were diagnosed according to the EAPD criteria. Results: DMFT did not show any significant difference between obese and normal weight children in both age groups. However, in 6–11 age group, obese children had lower dft and the difference was statistically significant (p<0.001). Median caries index values and MIH prevelance among the obese and normal weight children found similar with deficient, insufficient and sufficient levels of serum 25(OH) D in both age groups. Conclusion: Our analyses provide no evidence to suggest that obese children are at increased risk for dental caries. Serum 25(OH)D concentrations would not seem to have a significant effect on dental caries and MIH in children.
Keywords
Obesity; Children; Vitamin D; Dental caries; MIH
Cite and Share
Gülçin Doğusal,Işıl Sönmez,Tolga Ünüvar. Evaluation of Serum 25(OH)D Levels in Obese and Normal-Weight Children with Carious and Hypomineralized Teeth. Journal of Clinical Pediatric Dentistry. 2021. 45(1);35-40.
References
1. Dye BA, Hsu K-LC, Afful J. Prevalence and Measurement of Dental Caries in Young Children. Pediatr Dent;37(3):200-216. 2015.
2. Kong Y, Zheng J, Zhang W, et al. The relationship between vitamin D receptor gene polymorphism and deciduous tooth decay in Chinese children. BMC Oral Health. 2017;17(1):111. doi:10.1186/s12903-017-0398-x
3. Li L-W, Wong HM, McGrath CP. Longitudinal Association between Obesity and Dental Caries in Adolescents. J Pediatr. 2017;189:149-154.e5. doi:10.1016/j.jpeds.2017.06.050
4. Kantovitz KR, Pascon FM, Rontani RMP, Gavião MBD. Obesity and dental caries—A systematic review. Oral Health Prev Dent;4(2):137-144. 2006.
5. Hooley M, Skouteris H, Boganin C, Satur J, Kilpatrick N. Body mass index and dental caries in children and adolescents: a systematic review of literature published 2004 to 2011. Syst Rev. 2012;1:57. doi:10.1186/2046-4053-1-57
6. Hayden C, Bowler JO, Chambers S, et al. Obesity and dental caries in children: a systematic review and meta-analysis. Community Dent Oral Epidemiol. 2013;41(4):289-308. doi:10.1111/cdoe.12014
7. Hall-Scullin EP, Whitehead H, Rushton H, Milsom K, Tickle M. A longitudinal study of the relationship between dental caries and obesity in late childhood and adolescence. J Public Health Dent. 2018;78(2):100-108. doi:10.1111/jphd.12244
8. Theodoratou E, Tzoulaki I, Zgaga L, Ioannidis JPA. Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ. 2014;348:g2035. doi:10.1136/bmj.g2035
9. Kühnisch J, Thiering E, Kratzsch J, et al. Elevated serum 25(OH)-vitamin D levels are negatively correlated with molar-incisor hypomineralization. J Dent Res. 2015;94(2):381-387. doi:10.1177/0022034514561657
10. Weerheijm KL. Molar incisor hypomineralisation (MIH). Eur J Paediatr Dent;4(3):114-120. 2003.
11. Lygidakis NA, Wong F, Jälevik B, Vierrou A-M, Alaluusua S, Espelid I. Best Clinical Practice Guidance for clinicians dealing with children presenting with Molar-Incisor-Hypomineralisation (MIH): An EAPD Policy Document. Eur Arch Paediatr Dent Off J Eur Acad Paediatr Dent. 2010;11(2):75-81. doi:10.1007/BF03262716
12. Brandão-Lima PN, Santos B da C, Aguilera CM, Freire ARS, Martins- Filho PRS, Pires LV. Vitamin D Food Fortification and Nutritional Status in Children: A Systematic Review of Randomized Controlled Trials. Nutrients. 2019;11(11). doi:10.3390/nu11112766
13. Karagüzel G, Dilber B, Çan G, Ökten A, Deger O, Holick MF. Seasonal Vitamin D Status of Healthy Schoolchildren and Predictors of Low Vitamin D Status. J Pediatr Gastroenterol Nutr. 2014;58(5). https://journals. lww.com/jpgn/Fulltext/2014/05000/Seasonal_Vitamin_D_Status_of_ Healthy.26.aspx
14. Akman AO, Tumer L, Hasanoglu A, Ilhan M, Caycı B. Frequency of vitamin D insufficiency in healthy children between 1 and 16 years of age in Turkey. Pediatr Int. 2011;53(6):968-973. doi:10.1111/j.1442-200X.2011.03486.x
15. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320(7244):1240-1243. doi:10.1136/bmj.320.7244.1240
16. Neyzi O, Bundak R, Gökçay G, et al. Reference Values for Weight, Height, Head Circumference, and Body Mass Index in Turkish Children. J Clin ResPediatr Endocrinol. 2015;7(4):280- 293. doi:10.4274/jcrpe.2183
17. World Health Organization. Oral Health Surveys: Basic Methods, International Classification of Diseases. 4th ed.; 1997.
18. Saggese G, Vierucci F, Prodam F, et al. Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians. Ital J Pediatr. 2018;44(1):51. doi:10.1186/s13052-018-0488-7
19. Willerhausen B, Blettner M, Kasaj A, Hohenfellner K. Association between body mass index and dental health in 1,290 children of elementary schools in a German city. Clin Oral Investig. 2007;11(3):195-200. doi:10.1007/ s00784-007-0103-6
20. Costacurta M, Di Renzo L, Bianchi A, Fabiocchi F, De Lorenzo A, Docimo R. Obesity and dental caries in paediatric patients. A cross-sectional study. Eur J Paediatr Dent ;12(2):112-116. 2011.
21. Kopycka-Kedzierawski DT, Auinger P, Billings RJ, Weitzman M. Caries status and overweight in 2- to 18-year-old US children: findings from national surveys. Community Dent Oral Epidemiol. 2008;36(2):157-167. doi:10.1111/j.1600-0528.2007.00384.x
22. Liang J-J, Zhang Z-Q, Chen Y-J, et al. Dental caries is negatively correlated with body mass index among 7-9 years old children in Guangzhou, China. BMC Public Health. 2016;16:638. doi:10.1186/s12889-016-3295-3 23. Chen D, Zhi Q, Zhou Y, Tao Y, Wu L, Lin H. Association between Dental Caries and BMI in Children: A Systematic Review and Meta-Analysis.Caries Res. 2018;52(3):230- 245. doi:10.1159/000484988
24. Köksal E, Tekçiçek M, Yalçin SS, Tuğrul B, Yalçin S, Pekcan G. Association between anthropometric measurements and dental caries in Turkish school children. Cent Eur J Public Health;19(3):147-151.2011.
25. Bulut H, Bulut G. The relationship between obesity and dental caries according to life style factors in schoolchildren: a case-control study. Acta Odontol Scand. Published online January 2020:1-7. doi:10.1080/00016357.2020.1720799
26. Vallogini G, Nobili V, Rongo R, et al. Evaluation of the relationship between obesity, dental caries and periodontal disease in adolescents. Eur J Paediatr Dent. 2017;18(4):268-272. doi:10.23804/ejpd.2017.18.04.02
27. de Jong-Lenters M, van Dommelen P, Schuller AA, Verrips EHW. Body mass index and dental caries in children aged 5 to 8 years attending a dental paediatric referral practice in the Netherlands. BMC Res Notes. 2015;8:738. doi:10.1186/s13104-015-1715-6
28. D’Mello G, Chia L, Hamilton SD, Thomson WM, Drummon BK. Childhood obesity and dental caries among paediatric dental clinic attenders. Int J Paediatr Dent. 2011;21(3):217-222. doi:10.1111/j.1365-263X.2011.01112.x
29. Macek MD, Mitola DJ. Exploring the association between overweight and dental caries among US children. Pediatr Dent;28(4):375-380. 2006.
30. Goodson JM, Tavares M, Wang X, et al. Obesity and dental decay: inference on the role of dietary sugar. PLoS One. 2013;8(10):e74461. doi:10.1371/ journal.pone.0074461
31. Sánchez-Pérez L, Irigoyen ME, Zepeda M. Dental caries, tooth eruption timing and obesity: a longitudinal study in a group of Mexican schoolchildren. Acta Odontol Scand. 2010;68(1):57-64. doi:10.3109/00016350903449367
32. Kumar S, Kroon J, Lalloo R, Kulkarni S, Johnson NW. Relationship between body mass index and dental caries in children, and the influence of socio-economic status. Int Dent J. 2017;67(2):91-97. doi:10.1111/idj.12259
33. Mellanby M, Pattison CL. THE ACTION OF VITAMIN D IN PREVENTING THE SPREAD AND PROMOTING THE ARREST OF CARIES IN CHILDREN. Br Med J. 1928;2(3545):1079-1082. doi:10.1136/bmj.2.3545.1079
34. Hujoel PP. Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis. Nutr Rev. 2013;71(2):88-97. doi:10.1111/j.1753-4887.2012.00544.x
35. Gyll J, Ridell K, Öhlund I, Karlsland Åkeson P, Johansson I, Lif Holgerson P. Vitamin D status and dental caries in healthy Swedish children. Nutr J.2018;17(1):11. doi:10.1186/s12937-018-0318-1
36. Schroth RJ, Rabbani R, Loewen G, Moffatt ME. Vitamin D and Dental Caries in Children. J Dent Res. 2016;95(2):173-179. doi:10.1177/0022034515616335
37. Herzog K, Scott JM, Hujoel P, Seminario AL. Association of vitamin D and dental caries in children: Findings from the National Health and Nutrition Examination Survey, 2005-2006. J Am Dent Assoc. 2016;147(6):413-420. doi:10.1016/j.adaj.2015.12.013
38. Ghanim A, Elfrink M, Weerheijm K, Mariño R, Manton D. A practical method for use in epidemiological studies on enamel hypomineralisation. Eur Arch Paediatr Dent. 2015;16(3):235-246. doi:10.1007/ s40368-015-0178-8
39. Gültekin A, Ozalp I, Hasanoğlu A, Unal A. Serum-25-hydroxycholecalciferol levels in children and adolescents. Turk J Pediatr. 1987;29(3):155-162.
40. Olmez D, Bober E, Buyukgebiz A, Cimrin D. The frequency of vitamin D insufficiency in healthy female adolescents. Acta Paediatr. 2006;95(10):1266-1269. doi:10.1080/08035250600580495
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