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Chronic Recurrent Multifocal Osteomyelitis Involving the Mandible – A Rare Case Report
1Oral and Maxillofacial Radiology University of Florida, College of Dentistry, Gainesville, FL 32611 USA
2Oral and Maxillofacial Radiology, Creighton University School of Dentistry, Omaha, NE 68178 USA
3Oral and Maxillofacial Radiology Joint Professor of Radiology, The University of Florida, FL 32611 USA
4Private practice, USA
*Corresponding Author(s): Abrar Alamoudi E-mail: Dr.abrar89@gmail.com
Chronic recurrent multifocal osteomyelitis (CRMO) is an uncommon, aseptic, autoinflammatory condition characterized by multifocal bone lesions with pain, swelling, and frequent exacerbations and remissions. It is noteworthy that these lesions occur without any identifiable etiology or microbiologic finding. The clavicle and metaphyses of the long bones are often involved whereas involvement of the mandible is considered rare. It is usually diagnosed by exclusion of other diseases. As it shares most of its features with the more commonly occurring infective osteomyelitis, patients are often unnecessarily subjected to prolonged courses of antibiotics, serial radiation exposures, and repeated bone biopsies.
We present a case of CRMO involving the mandible. Our primary objective is to demonstrate the clinical features of this uncommon disorder, highlighting the radiographic appearance. Familiarity with this condition among radiologists greatly increases the likelihood for early diagnosis and formulating an appropriate treatment plan.
Chronic multifocal osteomyelitis; Multifocal osteomyelitis; Chronic osteomyelitis
Abrar Alamoudi,Niranzena Panneer Selvam,Deeba Kashtwari,Axel Ruprecht,Matthew Hansen. Chronic Recurrent Multifocal Osteomyelitis Involving the Mandible – A Rare Case Report. Journal of Clinical Pediatric Dentistry. 2021. 45(4);273-277.
1. Giedion A, Holthusen W, Masel LF, Vischer D. Subacute and chronic “symmetrical” osteomyelitis. Ann Radiol ;15(3):329–42. 1972.
2. Monsour PA, Dalton JB. Chronic recurrent multifocal osteomyelitis involving the mandible: case reports and review of the literature. Dento-maxillofac Radiol.;39(3):184–90. 2010.
3. Roderick MR, Sen ES, Ramanan AV. Chronic recurrent multifocal osteo-myelitis in children and adults: current understanding and areas for development. Rheumatol.;57(1):41–8. 2018.
4. Kumar TKJ, Salim J, Shamsudeen TJ. Chronic Recurrent Multifocal Osteomyelitis–A Rare Clinical Presentation and Review of Literature. J Orthop Case Rep.;8(3):3–6. 2018.
5. Jelušić M, Čekada N, Frković M, et al. Chronic Recurrent Multifocal Osteomyelitis (CRMO) and Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) Syndrome–Two Presentations of the Same Disease? Acta Dermatovenerol Croat.;26(3):212–9. 2018.
6. Job-Deslandre C, Krebs S, Kahan A. Chronic recurrent multifocal osteomyelitis: five-year outcomes in 14 pediatric cases. Jt Bone Spine.;68(3):245– 51. 2001.
7. Iyer R, Thapa M, Chew F. Chronic recurrent multifocal osteomyelitis:Review. Am J Roentgenol.;196:87–91. 2011.
8. Taddio A, Ferrara G, Insalaco A, et al. Dealing with Chronic Non-Bacterial Osteomyelitis: a practical approach. Pediatr Rheumatol Online J.;15(1):87. 2017.
9. Taddio A, Zennaro F, Pastore S, Cimaz R. An Update on the Pathogenesis and Treatment of Chronic Recurrent Multifocal Osteomyelitis in Children. Paediatr Drugs.;19(3):165–72. 2017.
10. Huber AM, Lam PY, Duffy CM, et al. Chronic recurrent multifocal osteomyelitis: clinical outcomes after more than five years of follow-up. J Pediatr.;141(2):198–203. 2002.
11. Buck FM, Treumann TC, Winiker H, Strobel K. Chronic recurrent multifocal osteomyelitis (CRMO) with symmetric involvement of both femora: X- ray, bone scintigram, and MR imaging findings in one case. J Magn Reson Imaging.;26(2):422–6. 2007.
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