Article Data

  • Views 983
  • Dowloads 246

Case Reports

Open Access

Chronic Recurrent Multifocal Osteomyelitis Involving the Mandible – A Rare Case Report

  • Abrar Alamoudi1,*,
  • Niranzena Panneer Selvam2
  • Deeba Kashtwari1
  • Axel Ruprecht3
  • Matthew Hansen4

1Oral and Maxillofacial Radiology University of Florida, College of Dentistry, Gainesville, FL 32611 USA

2Oral and Maxillofacial Radiology, Creighton University School of Dentistry, Omaha, NE 68178 USA

3Oral and Maxillofacial Radiology Joint Professor of Radiology, The University of Florida, FL 32611 USA

4Private practice, USA

DOI: 10.17796/1053-4625-45.4.10 Vol.45,Issue 4,October 2021 pp.273-277

Published: 01 October 2021

*Corresponding Author(s): Abrar Alamoudi E-mail: Dr.abrar89@gmail.com

Abstract

Chronic recurrent multifocal osteomyelitis (CRMO) is an uncommon, aseptic, autoinflammatory condition characterized by multifocal bone lesions with pain, swelling, and frequent exacerbations and remissions. It is noteworthy that these lesions occur without any identifiable etiology or microbiologic finding. The clavicle and metaphyses of the long bones are often involved whereas involvement of the mandible is considered rare. It is usually diagnosed by exclusion of other diseases. As it shares most of its features with the more commonly occurring infective osteomyelitis, patients are often unnecessarily subjected to prolonged courses of antibiotics, serial radiation exposures, and repeated bone biopsies.

We present a case of CRMO involving the mandible. Our primary objective is to demonstrate the clinical features of this uncommon disorder, highlighting the radiographic appearance. Familiarity with this condition among radiologists greatly increases the likelihood for early diagnosis and formulating an appropriate treatment plan.

Keywords

Chronic multifocal osteomyelitis; Multifocal osteomyelitis; Chronic osteomyelitis

Cite and Share

Abrar Alamoudi,Niranzena Panneer Selvam,Deeba Kashtwari,Axel Ruprecht,Matthew Hansen. Chronic Recurrent Multifocal Osteomyelitis Involving the Mandible – A Rare Case Report. Journal of Clinical Pediatric Dentistry. 2021. 45(4);273-277.

References

1. Giedion A, Holthusen W, Masel LF, Vischer D. Subacute and chronic “symmetrical” osteomyelitis. Ann Radiol ;15(3):329–42. 1972.

2. Monsour PA, Dalton JB. Chronic recurrent multifocal osteomyelitis involving the mandible: case reports and review of the literature. Dento-maxillofac Radiol.;39(3):184–90. 2010.

3. Roderick MR, Sen ES, Ramanan AV. Chronic recurrent multifocal osteo-myelitis in children and adults: current understanding and areas for development. Rheumatol.;57(1):41–8. 2018.

4. Kumar TKJ, Salim J, Shamsudeen TJ. Chronic Recurrent Multifocal Osteomyelitis–A Rare Clinical Presentation and Review of Literature. J Orthop Case Rep.;8(3):3–6. 2018.

5. Jelušić M, Čekada N, Frković M, et al. Chronic Recurrent Multifocal Osteomyelitis (CRMO) and Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) Syndrome–Two Presentations of the Same Disease? Acta Dermatovenerol Croat.;26(3):212–9. 2018.

6. Job-Deslandre C, Krebs S, Kahan A. Chronic recurrent multifocal osteomyelitis: five-year outcomes in 14 pediatric cases. Jt Bone Spine.;68(3):245– 51. 2001.

7. Iyer R, Thapa M, Chew F. Chronic recurrent multifocal osteomyelitis:Review. Am J Roentgenol.;196:87–91. 2011.

8. Taddio A, Ferrara G, Insalaco A, et al. Dealing with Chronic Non-Bacterial Osteomyelitis: a practical approach. Pediatr Rheumatol Online J.;15(1):87. 2017.

9. Taddio A, Zennaro F, Pastore S, Cimaz R. An Update on the Pathogenesis and Treatment of Chronic Recurrent Multifocal Osteomyelitis in Children. Paediatr Drugs.;19(3):165–72. 2017.

10. Huber AM, Lam PY, Duffy CM, et al. Chronic recurrent multifocal osteomyelitis: clinical outcomes after more than five years of follow-up. J Pediatr.;141(2):198–203. 2002.

11. Buck FM, Treumann TC, Winiker H, Strobel K. Chronic recurrent multifocal osteomyelitis (CRMO) with symmetric involvement of both femora: X- ray, bone scintigram, and MR imaging findings in one case. J Magn Reson Imaging.;26(2):422–6. 2007.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 2.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time

Conferences

Top