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Chronic Recurrent Multifocal Osteomyelitis Involving the Mandible – A Rare Case Report

  • Abrar Alamoudi1,*,
  • Niranzena Panneer Selvam2
  • Deeba Kashtwari1
  • Axel Ruprecht3
  • Matthew Hansen4

1Oral and Maxillofacial Radiology University of Florida, College of Dentistry, Gainesville, FL 32611 USA

2Oral and Maxillofacial Radiology, Creighton University School of Dentistry, Omaha, NE 68178 USA

3Oral and Maxillofacial Radiology Joint Professor of Radiology, The University of Florida, FL 32611 USA

4Private practice, USA

DOI: 10.17796/1053-4625-45.4.10 Vol.45,Issue 4,October 2021 pp.273-277

Published: 01 October 2021

*Corresponding Author(s): Abrar Alamoudi E-mail:


Chronic recurrent multifocal osteomyelitis (CRMO) is an uncommon, aseptic, autoinflammatory condition characterized by multifocal bone lesions with pain, swelling, and frequent exacerbations and remissions. It is noteworthy that these lesions occur without any identifiable etiology or microbiologic finding. The clavicle and metaphyses of the long bones are often involved whereas involvement of the mandible is considered rare. It is usually diagnosed by exclusion of other diseases. As it shares most of its features with the more commonly occurring infective osteomyelitis, patients are often unnecessarily subjected to prolonged courses of antibiotics, serial radiation exposures, and repeated bone biopsies.

We present a case of CRMO involving the mandible. Our primary objective is to demonstrate the clinical features of this uncommon disorder, highlighting the radiographic appearance. Familiarity with this condition among radiologists greatly increases the likelihood for early diagnosis and formulating an appropriate treatment plan.


Chronic multifocal osteomyelitis; Multifocal osteomyelitis; Chronic osteomyelitis

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Abrar Alamoudi,Niranzena Panneer Selvam,Deeba Kashtwari,Axel Ruprecht,Matthew Hansen. Chronic Recurrent Multifocal Osteomyelitis Involving the Mandible – A Rare Case Report. Journal of Clinical Pediatric Dentistry. 2021. 45(4);273-277.


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