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Open AccessA Comparative Quantitative Assessment of Salivary Iga and Alpha Amylase in Caries Free and Caries Active Children
A Comparative Quantitative Assessment of Salivary Iga and Alpha Amylase in Caries Free and Caries Active Children
1Department of Pedodontics and Preventive Dentistry, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India
2Department of Pedodontics and Preventive Dentistry, Inderprastha Dental College and Hospital, Ghaziabad, Uttar Pradesh, India
3Department of Pedodontics and Preventive Dentistry, Buddha Institute of Dental Sciences and Hospital, Kankarbagh, Patna, Bihar, India
4Department of Pedodontics and Preventive Dentistry, Institute of Dental Sciences and Technologies, Modinagar, Uttar Pradesh, India
*Corresponding Author(s): Dipanshu Kumar E-mail: drdipanshu.kumar@gmail.com
Abstract
Objectives: The aim of the study was to assess the salivary IgA (immunoglobulin A) and alpha amylase levels in the unstimulated whole saliva samples of caries-free and caries-active children and correlate it with the caries status and age. Study design: The salivary IgA and amylase was investigated in 100 children in the range of 8–12 years divided in two groups, control group (DMFT and/or deft = 0) and study group (DMFT/deft score ≥5). The salivary IgA was measured using kit based on two-site sandwich enzyme immunoassay principle and amylase was estimated using the vitro amyl slides. Results :The mean salivary IgA and amylase levels in the saliva of the children in the control group was found to be significantly increased (p=.001 and p=.014 respectively) whereas the relationship between salivary IgA and amylase levels in the saliva of the children was found to be insignificant with the age (p=.392 and p=.306 respectively). Conclusions: The results indicated that salivary IgA and amylase levels in saliva increased significantly in caries free children and the level of salivary IgA and alpha amylase has no significant relation with the age of the children.
Keywords
Dental caries; Unstimulated whole saliva; Enzyme linked immunosorbent assay; Salivary IgA; Amylase
Cite and Share
Asib Ahmad,Dipanshu Kumar,Aparna Singh,Siddharth Anand,Nidhi Agarwal,Riyaz Ahmad. A Comparative Quantitative Assessment of Salivary Iga and Alpha Amylase in Caries Free and Caries Active Children. Journal of Clinical Pediatric Dentistry. 2021. 45(5);323-329.
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