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Original Research

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Clinical and Radiographic Evaluation of the Effectiveness of Formocresol, Mineral Trioxide Aggregate, Portland Cement, and Enamel Matrix Derivative in Primary Teeth Pulpotomies: A Two Year Follow-Up

  • Ceren Yildirim1,*,
  • Feridun Basak1
  • Ozlem Marti Akgun1
  • Gunseli Guven Polat1
  • Ceyhan Altun1

1Gulhane Medical Academy, Pediatric Dentistry Department, Ankara, Turkey

DOI: 10.17796/1053-4628-40.1.14 Vol.40,Issue 1,January 2016 pp.14-20

Published: 01 January 2016

*Corresponding Author(s): Ceren Yildirim E-mail: cerenk.yildirim@gmail.com

Abstract

Objective: The aim of this study was to evaluate and to compare clinical and radiographic outcomes of 4 materials (formocresol, mineral trioxide aggregate (MTA), Portland cement and enamel matrix derivative) using in primary teeth pulpotomies. Study Design: Sixty-five patients aged 5–9 years (32 female, 33 male) were included in this study. A total of 140 primary first and second molars with deep caries were treated with pulpotomy. All teeth were then restored with stainless steel crowns. The treated teeth were evaluated clinically and radiographically at 3, 6, 12, 18 and 24 months. Results: At 24 months, the clinical success rates of formocresol, MTA, Portland cement, and enamel matrix derivative were 96.9%, 100%, 93.9%, and 93.3%, respectively. The corresponding radiographic success rates were 84.4%, 93.9%, 86.7% and 78.1%, respectively. Conclusion: Although there were no statistically significant differences in clinical and radiographic success rates among the 4 groups, MTA appears to be superior to formocresol, Portland cement, and enamel matrix derivative as a pulpotomy agent in primary teeth.

Keywords

Pulpotomy, Formocresol, Mineral trioxide aggregate, Portland cement, Enamel matrix derivative

Cite and Share

Ceren Yildirim,Feridun Basak,Ozlem Marti Akgun,Gunseli Guven Polat,Ceyhan Altun. Clinical and Radiographic Evaluation of the Effectiveness of Formocresol, Mineral Trioxide Aggregate, Portland Cement, and Enamel Matrix Derivative in Primary Teeth Pulpotomies: A Two Year Follow-Up. Journal of Clinical Pediatric Dentistry. 2016. 40(1);14-20.

References

1. Dean JA, Avery DR, Mcdonald RE. Treatment of deep caries, vital pulp exposure, and pulpless teeth. Dentistry for the Child and Adolescent. 9th ed. Mosby Elsevier, Missouri, United Kingdom; 343-365, 2011.

2. Pashley DH, Walton RE, Slavkin HC. Pediatric Endodontics. Endodon-tics, 5th edn. BC Decker Inc, Hamilton, ON, Canada; 25-38, 2002.

3. Fuks AB. Pulp therapy for the primary and young permanent dentitions. Dent Clin North Am 44: 571-596, 2000.

4. Koshy S, Love RM. Endodontic treatment in the primary dentition. Aust Endod J 30: 59-68, 2004.

5. Ranly DM. Pulpotomy therapy in primary teeth, new modalities for old rationales. Pediatr Dent 16: 403-406, 1994.

6. Srinivasan V, Patchett L, Waterhouse P. Is there life after Buckley’s Formocresol? Part I, A narrative review of alternative interventions and materials. Int J Paediatr Dent 16: 117-127, 2006.

7. Torabinejad M, Chivian N. Clinical application of mineral trioxide aggre-gate. J Endod 25: 197-205, 1999.

8. Robertsa HW, Tothb JM, Berzinsc DW, Charltond DG. Mineral trioxide aggregate material use in endodontic treatment, A review of the literature. Dent Mater 24: 149-164, 2008.

9. Tenório de Franca TR, da Silva RJ, Sedycias de Queiroz M, Aguiar CM. Arsenic content in Portland cement, a literature review. Indian J Dent Res 21: 591-595, 2010.

10. Danesh G, Dammaschke T, Gerth HU, Zandbiglari T, Schäfer E. A comparative study of selected properties of ProRoot mineral trioxide aggregate and two Portland cements. Int Endod J 39: 213-219, 2006.

11. Saidon J, He J, Zhu Q, Safavi K, Spangberg L. Cell and tissue reactions to mineral trioxide aggregate and Portland cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95: 483-489, 2003.

12. Song JS, Mante FK, Romanow WJ, Kim S. Chemical analysis of powder and set forms of Portland cement, gray ProRoot MTA, white ProRoot MTA, and gray MTA-Angelus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:809-815, 2006.

13. Conti TR, Sakai VT, Fornetti AP, Moretti AB, Oliveira TM, Lourenço Neto N, Machado MA, Abdo RC. Pulpotomies with Portland cement in human primary molars. J Appl Oral Sci 17: 66-69, 2009.

14. Sabbarini J. Alternative interventions to formocresol as a pulpotomy medicament in primary dentition, a review of the literature. Smile 8: 6-16, 2008.

15. Miron RJ, Hedbom E, Ruggiero S, Bosshardt DD, Zhang Y, Mauth C, Gemperli AC, Iizuka T, Buser D, Sculean A. Premature osteoblast clustering by enamel matrix proteins induces osteoblast differentiation through up-regulation of connexin 43 and N-cadherin. PLoS One 6: 233- 275, 2011.

16. Casas ML, Kenny DJ, Johnston DH, Judd PL. Long-term outcomes of primary molar ferric sulphate pulpotomy and root canal therapy. Pediatr Dent 26: 44-48, 2004.

17. Agamy HA, Bakry NS, Mounir MMF, Avery DR. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpoto-mized primary teeth. Pediatr Dent 26: 302-309, 2004.

18. Holan G, Eidelman E, Fuks A. Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol. Pediatr Dent 27: 129-136, 2005.

19. Ekstrand KR, Ricketts DNJ, Kidd EAM. Reproducibility and accuracy of three methods for assessment of demineralisation depth on the occlusal surface, An in vitro examination. Caries Res 31: 224-231, 1997.

20. Huth K, Paschos E, Hajek-Al-Khatar N, Hollweck R, Crispin A, Hickel R, Folwacany M. Effectiveness of 4 pulpotomy techniques-randomized controlled trial. J Dent Res 84: 1144-1148, 2005.

21. Sabbarini J, Mohamed A, Wahba N, El-Meligy O, Dean J. Comparison of enamel matrix derivative versus formocresol as pulpotomy agents in the primary dentition. J Endod 34: 284-287, 2008.

22. Haralabakis NB, Yiagtzis SC, Toutountzakis NM. Premature or delayed exfoliation of deciduous teeth and root resorption and formation. Angle Orthod 64: 151-157, 1994.

23. Farooq NS, Coll JA, Kuwabara A, Shelton P. Success rates of formocresol pulpotomy and indirect pulp therapy in the treatment of deep dentinal caries in primary teeth. Pediatr Dent 22: 278-286, 2000.

24. Waterhouse PJ, Nunn JH, Whithworth JN. An investigation of the relative efficacy of Buckley’s formocresol and calcium hydroxide in primary molars vital pulp therapy. Br Dent J 188: 32-36, 2000.

25. Ibricevic H, Al-Jame Q. Ferric sulfate as pulpotomy agent in primary teeth, twenty month clinical follow-up. J Clin Pediatr Dent 24: 269-272, 2000.

26. Ansari G, Ranjpour M. Mineral trioxide aggregate and formocresol pulpotomy of primary teeth, a 2-year follow-up. Int Endod J 43: 413-418, 2010.

27. Mortazavi M, Mesbahi M, Azar MR, Ansari G. MTA Pulpotomy in Primary Molars, A Prospective Study. Res J Biol Sci 4: 599-603, 2009.

28. Conti TR, Sakai VT, Fornetti AP, Moretti AB, Oliveira TM, Lourenço Neto N, Machado MA, Abdo RC. Pulpotomies with Portland Cement In Human Primary Molars. J Appl Oral Sci 17: 66-69, 2009.

29. 29.Sakai VT, Moretti AB, Oliveira TM, Fornetti AP, Santos CF, Machado MA, Abdo RC. Pulpotomy of human primary molars with MTA and Port-land cement, a randomised controlled trial. Br Dent J 207: 128-129, 2009.

30. Havale R, Anegundi RT, Indushekar K, Sudha P. Clinical and radio-graphic evaluation of pulpotomies in primary molars with formocresol, glutaraldehyde and ferric sulphate. Oral Health Dent Manag 12: 24-31, 2013.

31. Myers DR, Pashley DH, Lake FT, Burnham D, Kalathoor S, Waters R. Systemic absorption of 14C-glutaraldehyde from glutaraldehyde-treated pulpotomy sites. Pediat Dent 8: 134-138, 1986.

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