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Revascularization Induced Maturogenesis of Non-Vital Immature Permanent Tooth Using Platelet-Rich Fibrin: A Case Report
1Department of Pedodontics and Preventive Dentistry, College of Dental Sciences
*Corresponding Author(s): N B Nagaveni E-mail: nagavenianurag@gmail.com
The aim of this report is to describe a novel method of revascularization therapy done in a non-vital, immature permanent tooth using Platelet-rich fibrin (PRF),in a recently developed scaffold material to overcome limitations associated with the traditional method of revascularization using natural blood clot. PRF prepared from autologous blood was placed in the root canal and patient was followed up regularly at one, three, six, nine and 12 months for detailed clinical and radiographic evaluation. At 12 months, radiographic examination revealed root elongation, root end closure, continued thickening of the root dentinal walls, obliteration of root canal space, and normal periradicular anatomy. However, more long term prospective trials and histological studies are highly needed before to testify PRF a panacea for the regenerative endodontic therapy in children.
immature teeth, platelet-rich-fibrin, revascularization
N B Nagaveni,Sidhant Pathak,P Poornima,Jooie S Joshi. Revascularization Induced Maturogenesis of Non-Vital Immature Permanent Tooth Using Platelet-Rich Fibrin: A Case Report. Journal of Clinical Pediatric Dentistry. 2016. 40(1);26-30.
1. El-Meligy OA, Avery DR. Comparison of apexification with mineral trioxide aggregate and calcium hydroxide. Pediatr Dent 28: 248-53, 2006.
2. Simon S, Rilliard R, Berdal A, Mchtou P. The use of mineral trioxide aggregate in one-visit apexification treatment: A prospective study. Int Endod J 40: 186-97, 2007.
3. Andreasen JO, Farik B, Munksgaard EC. Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture. Dent Traumatol 18: 134-7, 2002.
4. Rosenberg B, Murray PE, Namerow K. The effect of calcium hydroxide root filling on dentin fracture strength. Dent Traumatol 23: 26-9, 2007.
5. Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis: New treatment protocol? J Endod 30: 196-200, 2004.
6. Choukroun J, Adda F, Schoeffler C, Vervelle A. Une opportunite en paro-implantologie: le PRF. Implantodontie 42: 55-63-2 2001.
7. Geeta IB, Galagali G, Kulkarni S, Suran P, Noushin F. A natural melio-rate: Revolutionary tissue engineering in endodontics. J Clin Diagn Res 7(11): 2644-6, 2013.
8. Nagaveni NB, Poornima P, Joshi JS, Pathak S, Nandini DB. Revascular-ization of immature, nonvital permanent tooth using Platelet-rich fibrin in children. Pediatr Dent 37; 1-6, 2015.
9. Shivanshankar VY, Johns DA, Vidyanath S, Kumar MR. Platelet rich fibrin in the revascularization of tooth with necrotic pulp and open apex. J Conserv Dent 15: 395-8, 2012.
10. Mishra N, Narang I, Mittal N. Platelet-rich fibrin mediated revitalization of immature necrotic tooth. Contemp Clin Dent 4: 412-5, 2013.
11. Keswani D, Pandey RK. Revascularization of an immature tooth with a necrotic pulp using platelet-rich fibrin: a case report. Inter Endod J 46: 1096-104, 2013.
12. Hoshino E, Kurihara-Ando N, Sato I, et al. In-vitro antibacterial suscep-tibility of bacteria taken from infected root dentine to a mixture of cipro-floxacin, metronidazole and minocycline. Int Endod J 29: 125-30, 1996.
13. Sato I, Ando-Kurihara N, Kota K, Iwaku M, Hoshino E. Sterilization of infected root-canal dentine by topical application of a mixture of cipro-floxacin, metronidazole and minocycline in situ. Int Endod J 29: 118-24, 1996.
14. Kim JH, Kim Y, Shin SJ, Park JW, Jung IU. Tooth discoloration of imma-ture permanent incisor associated with triple antibiotic therapy: A case report. J Endod 36: 1086-91, 2010.
15. Petrino JA, Boda KK, Shambarger S, Bowles WR, McClanahan SB. Challenges in regenerative endodontics: A case series. J Endod 36: 536- 41, 2010.
16. Reynolds K, Johnson JD, Cohenca N. Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discoloration: a case report. Int Endod J 42: 84-92, 2009.
17. Huang GT, Sonoyama W, Liu Y, Liu H, Wang S, Shi S. The hidden trea-sure in apical papilla: The potential role in pulp/dentin regeneration and bioroot engineering. J Endod 34: 645-51, 2008.
18. Hargreaves K, Geisler T, Henry M. Regeneration potential of the perma-nent tooth: what does the future hold? J Endod 34: 51-6, 2008.
19. Huang FM, Yang SF, Zhao JH, Chang YC. Platelet-rich fibrin increases proliferation and differentiation of human dental pulp cells. J Endod 36:1628-32, 2010.
20. Chueh LH, Huang GT. Immature teeth with periradicular periodontitis or abscess undergoing apexogenesis: a paradigm shift. J Endod 32: 1205-13, 2006.
21. Wang X, Thibodeau B, Trope M, Trope M, Lin LM, Huang GT. Histo-logic characterization of regenerated tissues in canal space after the revi-talization /revascularization procedure of immature dog teeth with apical periodontitis. J Endod 36: 56-63, 2010.
22. Trope M. Treatment of the immature teeth with non-vital pulps and apical periodontitis. Dent Clin North Am. 54: 313-24, 2010.
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