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Original Research

Open Access

Effect of Fluoride Varnish on Enamel Remineralization in Anterior Teeth with Molar Incisor Hypomineralization

  • Manuel Restrepo1,*,
  • Fabiano Jeremias1
  • Lourdes Santos-Pinto1
  • Rita CL Cordeiro1
  • Angela CC Zuanon1

1Department of Orthodontics and Pediatric Dentistry, Araraquara Dental School,Univ Estadual Paulista (Unesp), Araraquara, São Paulo, Brazil

DOI: 10.17796/1053-4628-40.3.207 Vol.40,Issue 3,May 2016 pp.207-210

Published: 01 May 2016

*Corresponding Author(s): Manuel Restrepo E-mail:


Objective: The objective of this study was to investigate the effect of fluoride varnish on remineralization of anterior teeth affected by Molar-Incisor Hypomineralization (MIH) by means of Quantitative Light-Induced Fluorescence- QLF. Study design: Fifty-one healthy 9 – 12- year-old children were selected according to different clinically diagnosed levels of MIH, proposed by the European Academy of Pediatric Dentistry (2003) (considering the most severe lesion per patient, n= 51 lesions), and randomly divided into two groups: (1) four applications of 5% NaF varnish, with one-week interval, and (2) usual home care- control. At each visit, the mean change in fluorescence and area of lesion were measured by QLF. The data were analyzed by repeated measures ANOVA and Tukey's test. Results: All patients showed enamel alterations in first permanent molars and incisors, frequently with two molars affected by MIH (41.1%). There was no statically significant difference in the mean of fluorescence and area of lesion between groups over the studied time. Conclusion: We observed no favorable effect on the remineralization of MIH lesions in anterior teeth after four applications of fluoride varnish.


Fluorescence; Fluoride; Molar Incisor Hypomineralization; Tooth remineralization

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Manuel Restrepo,Fabiano Jeremias,Lourdes Santos-Pinto,Rita CL Cordeiro,Angela CC Zuanon. Effect of Fluoride Varnish on Enamel Remineralization in Anterior Teeth with Molar Incisor Hypomineralization. Journal of Clinical Pediatric Dentistry. 2016. 40(3);207-210.


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