Article Data

  • Views 824
  • Dowloads 163

Original Research

Open Access

Degradation of Resin Restorative Materials by Streptococcus Mutans: A Pilot Study

  • Ankit K Gautam1,*,
  • Ruchi Thakur1
  • Shashikiran N D1
  • Singla Shilpy1
  • Nikita Agarwal1
  • Shilpi Tiwari1

1Department of Paedodontics and Preventive Dentistry People’s College of Dental Sciences and Research Centre, India

DOI: 10.17796/1053-4628-41.3.225 Vol.41,Issue 3,May 2017 pp.225-227

Published: 01 May 2017

*Corresponding Author(s): Ankit K Gautam E-mail:


Objective: To evaluate the degradation of three resin based restorative materials by S Mutans. Study design: Class I cavity was prepared in extracted premolars and were randomly divided into 3 groups (Group I – Conventional composite (CC), Group II – Resin Modified GIC and Group III–Giomer). Teeth were then restored by respective restorative material and equally divided in two subgroups (Control and Experimental). Experiment subgroup samples were then incubated in 2 ml of BHI with 1:10 dilution of SM (MTCC-497) grown overnight in BHI whereas control subgroup samples were incubated in BHI without SM. The incubation solution was collected at 2,14 and 30 days interval, and the analysis for identification and quantification of Bis-HPPP was done by High performance Liquid Chromatography. Results: Statistical analysis of the collected data revealed a statistically increased Bis HPPP production in the presence of SM in all the tested materials, with minimum in Resin Modified GIC and a maximum in Conventional Composite (CC). Conclusion: SM degrades the resin based restorative materials & among the tested materials Resin Modified GIC appears to be most Biostable.


Resin, S mutans, degradation, High performance liquid chromatography

Cite and Share

Ankit K Gautam,Ruchi Thakur,Shashikiran N D,Singla Shilpy,Nikita Agarwal,Shilpi Tiwari. Degradation of Resin Restorative Materials by Streptococcus Mutans: A Pilot Study. Journal of Clinical Pediatric Dentistry. 2017. 41(3);225-227.


1. Jaffer F , Finer Y, and Santerre JP. Interactions between resin monomers and commercial composite resins with human saliva derived esterases. Biomaterials, 23(7):1707-19, 2002.

2. Khalichi P, Singh J, Cvitkovitch DG, Santerre JP. The influence of trieth-ylene glycol derived from dental composite resins on the regulation of Streptococcus mutans gene expression. Biomaterials, 30(4):452-459, 2009.

3. Murray PE, Windsor LJ, Smyth TW, Hafez AA, Cox CF. Analysis of pulpal reactions to restorative procedures, materials, pulp capping, and future therapies. Crit Rev Oral Biol Med. 13(6):509-520, 2002.

4. Burke F, Wilson N, Cheung S, Mjor AI. Influence of patient factors on age of restorations at failure and reasons for their placement and replacement. J Dent, 29(5):317-324,2001.

5. Mjor IA, Dahl JE, Moorhead JE. Age of restorations at replacement in permanent teeth in general dental practice. ActaOdontolScand, 58(3):97-101, 2000.

6. Santerre, J. P., L. Shajii, and B. W. Leung. Relation of dental composite formulations to their degradation and the release of hydrolyzed polymer-ic-resin-derived products. Crit Rev Oral Biol Med, 12(2):136-151, 2001.

7. Finer Y, Santerre JP. The influence of resin chemistry on a dental composite biodegradation. J Biomed Mater Res, 69A:233-246, 2004.

8. Msitra S. Curing reactions of glass-ionomer materials. In: Hunt PR, ed. Glass-ionomers: The next generation. Proceedings of the 2nd Interna-tional Symposium on Glass ionomers. Philadelphia, 13-23, 1994.

9. Kermanshahi S, Santerre JP, Cvitkovitch DG, Finer Y. Biodegradation of resin-dentin interfaces increases bacterial microleakage. J Dent Res, 89(9):996-01, 2010.

10. Brannstrom M. Communication between the Oral Cavity and the Dental-Pulp Associated with Restorative Treatment. Oper Dent, 9(2):57-68, 1984.

11. Bourbia M, Ma D, Cvitkovitch DG, Santerre JP, Finer Y. Cariogenic bacteria degrade dental resin composites and adhesives. J Dent Res, 92:989-994, 2013.

12. Shokati B, Tam LE, Santerre JP, Finer Y. Effect of salivary esterase on the integrity and fracture toughness of the dentin-resin interface. J Biomed Mater Res B Appl Biomater, 94(1):230-7, 2010.

13. Zhu H, Liu M, Sumby P, Lei B. The Secreted Esterase of Group A Strep-tococcus Is Important for Invasive Skin Infection and Dissemination in Mice. Infect Immun, 77(12):5225-32, 2009.

14. Borges MA, Matos IC, Mendes LC, Gomes AS, Miranda MS. Degrada-tion of polymeric restorative materials subjected to a high caries chal-lenge. Dent Mater, 27(3):244-52, 2011.

15. Fucio SB, Carvalho FG, Sobrinho LC, Sinhoreti MA, Puppin-Rontani RM . The influence of 30-day-old Streptococcus mutans biofilm on the surface of esthetic restorative materials–An in vitro study. J Dent, 36(10):833-9, 2008.

16. Gregson KS, Shih H, Gregory RL (2012). The impact of three strains of oral bacteria on the surface and mechanical properties of a dental resin material. Clin Oral Investig, 16(4):1095-103, 2012.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 1.8 (2023) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time