Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Effect of Sedation with Midazolam and Time to Discharge among Pediatric Dental Patients
1Department of Pediatric Dentistry, The Maurice and Gabriela Goldscleger School of Dental Medicine, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
DOI: 10.17796/1053-4628-41.5.384 Vol.41,Issue 5,September 2017 pp.384-387
Published: 01 September 2017
*Corresponding Author(s): Sigalit Blumer E-mail: blumer@012.net.il
The aim of this study was to examine the recovery time of children who underwent conscious sedation with oral or rectal midazolam. Study design: The medical files in the Department of Pediatric Dentistry of all the children who underwent conscious sedation with midazolam between 3/2013-4/2016 were examined. The total duration of sedation and time to discharge were calculated. Descriptions of the children’s behavior before and during sedation were compared. Results: The files of 120 children were retrieved. They included 64 girls, mean (± standard deviation) age 5.7 ± 2.67 years and 56 boys, mean age 4.9 ±1.06 years. The mean weight for the entire cohort was 18.7 ± 5.2 kg. Eighty-one children (67.5%) received oral sedation and 39 (32.5%) received rectal sedation. The mean total duration of sedation was 105 ± 26 min, and the mean time to discharge after treatment was 55:17 ± 22:30 min. A hundred and seven children exhibited positive behavior before undergoing sedation, but the behavior deteriorated during sedation in 36 cases. Conclusion: The time to discharge post-midazolam sedation correlated to the child’s age and weight and total amount of administered midazolam. Sedation negatively affected behavior in 43.6% of the cases.
sedation, midazolam, time to recovery, behavior
Sigalit Blumer,Benjamin Peretz,Gali Zisman,Tal Ratson. Effect of Sedation with Midazolam and Time to Discharge among Pediatric Dental Patients. Journal of Clinical Pediatric Dentistry. 2017. 41(5);384-387.
1. Avery DR, Dean JA. McDonald RE. Pharmacologic management of patient behavior. In: Dentistry for the Child and Adolescent. 9th edn. St. Louis, MO: Mosby Co; 253-276, 2011.
2. American Academy of Pediatric Dentistry. Clinical Affairs Committee-Behavior Management Subcommittee. Guideline on Behavior Guidance for the Pediatric Dental Patient. Pediatr Dent 37: 57-70, 2015.
3. Malamed SF. Sedation: A Guide to Patient Management. 5th edn. New York, NY: CV Mosby-Year Book Inc; 2005.
4. Peretz B, Kharouba J, Somri M. A comparison of two different dosages of oral midazolam in the same pediatric dental patients. Pediatr Dent 36: 228-232, 2014.
5. Papineni A, Lourenço-Matharu L, Ashley PF. Safety of oral midazolam sedation use in paediatric dentistry: a review. Int J Paediatr Dent 24: 2-13, 2014.
6. Tolksdorf W, Eick C. Rectal, oral and nasal premedication using midazolam in children aged 1-6 years. A comparative clinical study. Anaesthetist 40: 661-667, 1991.
7. Flaitz CM, Whitmire HC Jr, Vance BJ, Hill JR. Dosani FZ. Postdischarge events occurring after pediatric sedation for dentistry. Pediatr Dent 36: 411-416, 2014.
8. American Academy of Pediatric Dentistry. Clinical Affairs Committee – Sedation and General Anesthesia Subcommittee. Guideline on use of anesthesia personnel in the administration of office-based deep sedation/general anesthesia to the pediatric dental patient. Pediatr Dent 34: 170-172, 2012.
9. Somri M, Parisinos CA, Kharouba J, Cherni N, Smidt A, Abu Ras Z, Darawshi G, Gaitini LA. Optimising the dose of oral midazolam sedation for dental procedures in children: a prospective, randomised, and controlled study. Int J Paediatr Dent 22: 271-279, 2012.
10. Kanto JH. Midazolam: the first water-soluble benzodiazepine. Pharmacology, pharmacokinetics and efficacy in insomnia and anesthesia. Pharmacotherapy 5: 138-155, 1985.
11. Primosch RE, Bender F. Factors associated with administration route when using midazolam for pediatric conscious sedation. ASDC J Dent Child 68: 233-238, 228, 2001.
Top