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Bioethical Issues in Conducting Pediatric Dentistry Clinical Research

  • Arturo Garrocho-Rangel1
  • Bernardino Cerda-Cristerna2
  • Amaury Pozos-Guillen1,*,

1Pediatric Dentistry Postgraduate Program, Faculty of Dentistry, San Luis Potosi University, San Luis Potosí, SLP, México

2Faculty of Dentistry, Veracruzana University (Rio Blanco), Orizaba, Ver., México

DOI: 10.17796/1053-4628-42.2.1 Vol.42,Issue 2,March 2018 pp.85-90

Published: 01 March 2018

*Corresponding Author(s): Amaury Pozos-Guillen E-mail: apozos@uaslp.mx

Abstract

Pediatric clinical research on new drugs and biomaterials involves children in order to create valid and generalizable knowledge. Research on vulnerable populations, such as children, is necessary but only admissible when researchers strictly follow methodological and ethical standards, together with the respect to human rights; and very especially when the investigation cannot be conducted with other population or when the potential benefits are specifically for that age group. Clinical research in Pediatric Dentistry is not an exception. The aim of the present article was to provide the bioethical principles (with respect to the child/parents' autonomy, benefit/risk analysis, and distributive justice), and recommendations, including informed consent, research ethics committees, conflict of interest, and the “equipoise” concept. Current and future worldwide oral health research in children and adolescents must be conducted incorporating their perspectives in the decision-making process as completely as possible. This concept must be carefully considered when a dental clinical study research is going to be planned and conducted, especially in the case of randomized controlled trials, in which children will be recruited as participants.

Keywords

Bioethical, Child, Clinical Research, Randomized Controlled Trial

Cite and Share

Arturo Garrocho-Rangel,Bernardino Cerda-Cristerna,Amaury Pozos-Guillen. Bioethical Issues in Conducting Pediatric Dentistry Clinical Research. Journal of Clinical Pediatric Dentistry. 2018. 42(2);85-90.

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