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Hereditary gingival fibromatosis: report of three cases

  • Lourenco Bozzo1
  • Maria Angela Naval Machado2
  • Oslei Paes de Almeida1
  • Marcio Ajudarte Lopes3
  • Ricardo D. Coletta1,*,

1Discipline of Oral Pathology, University of Campinas Dental School, Piracicaba-SP, Brazil

2Post-doctoral Discipline of Periodontology, University of Campinas Dental School, Piracicaba-SP, Brazil

3Discipline of Oral Medicine, University of Campinas Dental School, Piracicaba-SP, Brazil.

DOI: 10.17796/jcpd.25.1.e254616x22403280 Vol.25,Issue 1,January 2001 pp.41-46

Published: 01 January 2001

*Corresponding Author(s): Ricardo D. Coletta E-mail: coletta@fop.unicamp.br

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Abstract

Three cases of generalized and severe HGF in young patients of the same family without other features are reported.The purpose of this article is to present documented cases and discuss the identification, treatment, and control of the disease. The histopathological characteristics of HGF are emphasized.

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Lourenco Bozzo,Maria Angela Naval Machado,Oslei Paes de Almeida,Marcio Ajudarte Lopes,Ricardo D. Coletta. Hereditary gingival fibromatosis: report of three cases. Journal of Clinical Pediatric Dentistry. 2001. 25(1);41-46.

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https://www.jocpd.com/articles/10.17796/jcpd.25.1.e254616x22403280

References

1. Bozzo L, Almeida OP, Scully C, Aidred MJ. Hereditary gingival fibromatosis report of an extensive four-generation pedigree. Oral Surg Oral Med Oral Pathol 78: 452-454, 1994.

2. Fletcher JP. Gingival abnormalities of genetic origin: a preliminary communication with special reference to hereditary generalized gingival fibromatosis. J Dent Res 45: 597-612, 1966.

3. Singer SL, Goldblatt J, Hallam LA, Winters JC. Hereditary gingival fibromatosis with a recessive mode of inheritance. Case reports. Aust Dent J 38: 427-432, 1993.

4. Araiche M, Brode H. A case of fibromatosis gingivae. Oral Surg 12: 1307-1310, 1959.

5. Becker W, Collings CK, Zimmerman ER, La Rosa MD, Singdahlsen D. hereditary gingival fibromatosis. J Oral Path 24: 313-318, 1967.

6. Gunhan 0, Gardner DG, Bostanci H, Gunhan M. Familial gingival fibromatosis with unusual histologic findings. J Periodontol 66:1008-1011, 1995.

7. Farrer-Brown G, Lucas RB, Winstock D. Familial gingival fibromatosis: an unusual pathology. J Oral Pathol 1: 76-83, 1972.

8. Shirasuna K, Okur M, Watatani K, Hayashido Y, Saka M, Matsuya T. Abnormal cellular property of fibroblasts from congenital gingival fibromatosis. J Oral Pathol 7: 381-385, 1989.

9. Oikarinen K, Salo T, Kaar M-L, Lahtela P, Altonen M. Hereditary gingival fibromatosis associated with growth hormone deficiency. Br J Oral Maxillofac Surg 28: 335-339, 1990.

10. Tipton DA, Dabbous MKh. Autocrine transforming growth factor j3 stimulation of extracellular matrix production by fibroblasts from fibrotic human gingiva. J Periodontol 69: 609-619, 1998.

11. Coletta RD, Almeida OP, Ferreira LR, Reynolds MA, Sauk JJ. Increase in expression of Hsp47 and collagen in hereditary gingival fibromatosis is modulated by stress and terminal procollagen N-propeptides. Conn Tis Res, 1999. (IN PRESS)

12. Coletta RD, Almeida OP, Graner E, Page RC, Bozzo L. Differential proliferation of fibroblasts cultured from hereditary gingival fibromatosis and normal gingiva. J Periodont Res 33: 469-475, 1998.

13. Coletta RD, Almeida OP, Reynolds MA, Sauk JJ. Alteration in expression of MMP-1 and MMP-2 but not TIMP-1 and TIMP-2 in hereditary gingival fibromatosis is mediated by TGF-pI autocrine stimulation. J Periodont Res 34:1-7,1999.

14. Cuestas-Carneiro R, Bornancini CA. Hereditary generalized gingival fibromatosis associated with hypertrichosis: report of five cases in one family. J Oral Maxillofac Surg 46: 415-420, 1988.

15. Ramon Y, Berman W, Bubis JS. Gingival fibromatosis combined with cherubism. Oral Surg 24: 435-448, 1967.

16. Hartsfield JK, Bixler D, Hazen RH. Gingival fibromatosis with sensoneural hearing loss: an autosomal dominant trait. Am J Med Genet 22: 623-627, 1985.

17. Skrinjaric I, Bacic M. Hereditary gingival fibromatosis: report on three families and dermatoglyphic analysis. J Periodont Res 24: 303-309, 1989.

18. Winter GB, Simpkiss JJ. Hypertrichosis with hereditary gingival hyperplasia. Arch Dis Child 49: 394-399, 1974.

19. Gorlin RJ, Cohen MM, Levin LS. Syndromes of the head and neck, 3rd Ed. New York, Oxford University Press; 847-858, 1990.

20. Nevin NC, Scally BG, Kemohan DC, Dodge JA. Hereditary gingival fibromatosis. J Ment Defic Res 15: 130-135, 1971.

21. Emerson TG. Hereditary gingival fibromatosis: a family pedigree of four generations. Oral Surg Oral Med Oral Pathol 19: 1-9, 1965.

22. Ball El. Case of gengivoma, or elephantiasis of the gingiva. J Periodont 12: 96-100, 1941.

23. Tipton DA, Howell KJ, Dabbous MK. Increased proliferation, collagen, and fibronectin production by hereditary gingival fibromatosis fibroblasts. J Periodontol 68: 524-530, 1997.

24. Mclndoe A, Smith BO. Congenital familial fibromatosis of the gums with the teeth as a probable etiological factor: report of an affected family. Brit J Plast Surg 11: 62-71,1958.

25. Bakaeen G, Scully C. Hereditary gingival fibromatosis in a family with the Zimmermann-Laband syndrome. J Oral Pathol Med 20: 457-459, 1991.

26. Zackin SJ, Weisberger D. Hereditary gingival fibromatosis: report of a family. J Oral Pathol 14: 828-836, 1961.

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