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Original Research

Open Access

Titanium penetration in human enamel after TiF4 application

  • Ana Beatriz Chevitarese1,*,
  • Orlando Chevitarese2
  • Leila Maria Chevitarese3
  • Paulo Bechara Dutra4

1Pedodontics, Federal University of Rio de Janeiro

2,Federal University of Rio de Janeiro


4Chemistry Institute, Federal University of Rio de Janeiro

DOI: 10.17796/jcpd.28.3.jn86252876j75053 Vol.28,Issue 3,July 2004 pp.253-256

Published: 01 July 2004

*Corresponding Author(s): Ana Beatriz Chevitarese E-mail:


The TiF4 application produces a titanium coating on enamel surface, reducing solubility in presence of

cariogenic challenge. However, it is not established if this titanium also penetrates inside the enamel.

The aim of this study was to evaluate in vitro the presence of this superficial coat and titanium penetration

into human sound and decayed enamel after TiF4 application. Twenty-four unerupted third

molars were mesiodistally cut and divided into two groups (GA - sound and GB – artificial decayed).

After a 4% TiF4 application, each sample was fractured longitudinally (occlusal-cervical). Through

microprobe analysis with energy dispersive spectrometer (EDS), titanium penetration could be

observed inside the enamel. The McNemar test (p=0.267) showed that there was no difference between

the groups analyzed regarding to titanium penetration, although in group A the titanium penetrated

more deeply (Wilcoxon test, p=0.047). It could be concluded that there was no difference between the

groups regarding the titanium penetration, but titanium penetrated more deeply into sound enamel

compared to artificially decayed enamel.

Cite and Share

Ana Beatriz Chevitarese,Orlando Chevitarese,Leila Maria Chevitarese,Paulo Bechara Dutra. Titanium penetration in human enamel after TiF4 application. Journal of Clinical Pediatric Dentistry. 2004. 28(3);253-256.


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