Article Menu

Export Article

More by Authors Links

Article Data

  • Views 617
  • Dowloads 150

Original Research

Open Access

Pediatric Liquid Medicaments – Do They Erode The Teeth Surface? An In Vitro Study: Part I

  • KL Girish Babu1
  • Kavita Rai2
  • Amitha M. Hedge2,*,

1Department of Pedodontics, The Oxford Dental College, Hospital and Research Centre, Hosur road, Bangalore-68, Karnataka, India

2Department of Pedodontics and Preventive Dentistry, A.B.Shetty Memorial Institute of Dental Sciences, Deraltakatta, Mangalore, Karnataka, India

DOI: 10.17796/jcpd.32.3.j22m7t8163739820 Vol.32,Issue 3,May 2008 pp.189-194

Published: 01 May 2008

*Corresponding Author(s): Amitha M. Hedge E-mail: drgirish77@yahoo.com amipedo@yahoo.co.in

PDF (400.31 kB) View Full-text

Abstract

The present study was conducted to investigate the endogenous erosive potential of some of the most com-monly used pediatric liquid medicaments in our day to day practice. Eight commonly used pediatric liquid medicaments were selected and their endogenous pH was measured using a pH electrode meter. Twenty four exfoliated or extracted primary teeth without any carious lesion/restorations, maintained in selected pedi-atric liquid medicaments were observed under SEM after 1 min, 10 mins and 8 hours of time intervals. The pH ranged between 6.05 (Salbutamol) to 6.77 (Paracetamol) which were acidic, whereas Theophylline had a basic pH of 7.71. The irregular pattern of pit –like erosion area were seen in all specimens, varying from site to site and probably depending on the prismatic versus aprismatic nature and composition of the affected enamel. In conclusion, all the pediatric liquid medicaments used in this study showed an erosive effect on the primary enamel surface irrespective of their pH when viewed under SEM.

J Clin Pediatr Dent 32(3): 189–194, 2008


Cite and Share

KL Girish Babu,Kavita Rai,Amitha M. Hedge. Pediatric Liquid Medicaments – Do They Erode The Teeth Surface? An In Vitro Study: Part I . Journal of Clinical Pediatric Dentistry. 2008. 32(3);189-194.

URL:

https://www.jocpd.com/articles/10.17796/jcpd.32.3.j22m7t8163739820

References

1. http://www.prnewswire.co.uk/cgi/news/release.

2. Addy M, Edgar WM, Embeny G, & Orchardson R. Tooth Wear & Sen-sitivity. Clinical Advances in Restorative Dentistry. Informal Health-care, 129, 2000.

3. Greenwood M, Feigal R, Messer H. Cariogenic Potential of Liquid Medications in Rats. Caries Res, 18: 447–449, 1984.

4. Weld GW. (Citation) The destructive energy of tincture chloride of iron on the teeth. Independent practitioner (Dental) viii: 373–374, 1886.

5. Stafne EC, Lovestedi SA. Dissolution of tooth substance by lemon juice and beverages and aids from some other sources. J Am Dent Assoc, 34: 586–592, 1947.

6. Smith BGN. Tooth wear-Etiology & diagnosis. Dental update, 10: 204–212, 1989.

7. Imfeld TN. Cariogenic cough medicines. Schweiz Monatsschr Zahn-heilkd 87: 773–777, 1977.

8. Mackie IC, Hobson P. Factor affecting the availability of sugar -free medicines for children- a survey in UK. Inter J Ped Dent, 3: 163–167, 1993.

9. Rekola M. In vivo Acid Production from Medicines & in Syrup Form. Caries Res, 23: 412–416, 1989.

10. Sharma A, Chandra S, Jaiswal JN, Bajpai VK. Effect of conditioning the enamel surface of primary teeth with citric acid: A SEM study. J Clin Pediatr Dent, 16: 207–212, 1996.

11. Curzon MEJ, Pollard M.A. (Citation) Nursing caries: the extent & nature of the problem: presented at the workshop on carbohydrates in infant nutrition & dental health. J. Dent Res, 30: 233–238, 1994.

12. Ali YA, Chandraee NJ, Khan A, Khan ZH. Prevalence of dental caries in the nursery school at Akola city. J Ind Soc Pedo Prev Dent, 16: 21–25, 1998.

13. Nunn JH, Ng SKF, Sharkey I, Coulthard M. The dental implications of chronic use of acidic medicines in medically compromised children. Pharm world Sci, 23: 118–9, 2001.

14. Mentes A. pH changes in dental plaque after using sugar free pediatric medicine. J Clin Pediatr Dent, 25: 307–312, 2001.

15. Robert IF and Robert GJ. Relationship between medicines sweetened with sucrose and dental disease. Br Med J, 2: 14–16, 1979.

16. Feigal RJ, Gleeson MC, Beckman TM, Greenwood ME. Dental caries related to liquid medication intake of young cardiac patients. J Dent Child, 54: 360–364, 1984.

17. Silverstone LA, Saxton CA, Dogon IL & Fejerskov O. Variations in the pattern of acid etching of human enamel examined by scanning elec-tron microscopy. Caries Res, 9: 373–387, 1975.

18. Grando LJ, Tames DR, Cardoso AC, Gabilan NH. In vitro study of enamel erosion caused by soft drinks and lemon juice in deciduous teeth analyzed by stereomicroscopy and scanning electron Microscopy. Caries Res, 30: 373–8, 1996.

19. Schweizer Hirt CM, Schait A. Schmid R. (Citation) Erosion & abrasion of the dental enamel. Experimental study. SSO: Schweiz Montasschr Zahnheilkd, 88: 497–529, 1978.

20. Meurman JH, Frank RM. Progression and surface ultra structure of in vitro caused erosive lesion in human & bovine enamel. Caries Res, 25: 81–87, 1991.

21. Shafer WG. A Textbook of Oral Pathology, 4th ed: Saunders company WB; 417, 1993.

22. Johansson AK, Sorvari R, Birkhed D, Meurman JH. Dental erosion in deciduous teeth- an in vivo & in vitro study. J Dent, 5: 333–40, 2001.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 2.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time

Conferences

Top