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Original Research

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Evaluation of Oral Hygiene Status, Salivary Characteristics and Dental Caries Experience in Acute Lymphoblastic Leukemic (ALL) Children

  • Hegde AM1,*,
  • Joshi S1
  • Rai K1
  • Shetty S1

1Department of Pedodontics and Preventive Children Dentistry, A.B. Shetty Memorial Institute of Dental Sciences, Derlakatte, Mangalore-575018, Karnataka, India.

DOI: 10.17796/jcpd.35.3.u5kx28q33m760834 Vol.35,Issue 3,May 2011 pp.319-323

Published: 01 May 2011

*Corresponding Author(s): Hegde AM E-mail: amipedo@yahoo.co.in saurabhjoshi2006@yahoo.co.in

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Abstract

Leukemia constitutes approximately 30% of all childhood cancers and Acute Lymphoblastic Leukemia (ALL) is the most common type of malignancy. Oral dryness, ulceration, increased dental decay seen is due to altered salivary flow rate and buffering capacity in these children. Oxidative stress may play an important role in the malignancies resulting in onset of inflammatory oral pathologies. Saliva constitutes first line of defense against free radical-mediated oxidative stress. The present study attempted to relate the oral health status, salivary flow rate, salivary pH, gingival health status, dental caries experience and total salivary antioxidant levels in ALL children. A total of 120 children aged 4-10 years (90 leukemic children, study group and 30 normal healthy siblings, control group) were divided into 4 groups of 30 each. Oral health status, gingival status and dental caries experience was recorded followed by un-stimulated saliva collection. Total antioxidant capacity of un-stimulated saliva was evaluated. The results depicted deterioration in oral health status, gingival status and increased dental caries experience in leukemic children. Salivary flow rate, salivary pH and total salivary antioxidant levels were lowered in leukemic children when compared with control group.

Keywords

Salivary Flow Rate, Dental Caries, Total Antioxidant Capacity (TAC), Acute Lymphoblastic Leukemia.

Cite and Share

Hegde AM,Joshi S,Rai K,Shetty S. Evaluation of Oral Hygiene Status, Salivary Characteristics and Dental Caries Experience in Acute Lymphoblastic Leukemic (ALL) Children. Journal of Clinical Pediatric Dentistry. 2011. 35(3);319-323.

URL:

https://www.jocpd.com/articles/10.17796/jcpd.35.3.u5kx28q33m760834

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