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Effect of Xylitol on Dental Caries and Salivary Streptococcus Mutans Levels among a Group of Mother-Child Pairs

  • Azza G Hanno1
  • Najlaa M Alamoudi1,*,
  • Abdullah S Almushayt1
  • Mohammed I Masoud1
  • Heba J Sabbagh1
  • Najat M Farsi1

1Department of Preventive Dental Sciences, Faculty of Dentistry, King Abdulaziz University

DOI: 10.17796/jcpd.36.1.d4g77616714w3372 Vol.36,Issue 1,January 2012 pp.25-30

Published: 01 January 2012

*Corresponding Author(s): Najlaa M Alamoudi E-mail: Naj_alam@yahoo.com

Abstract

Recent researches have focused on xylitol as convenient and effective method to inhibit cariogenic bacteria. The purpose of the present study is to assess the effect of xylitol on plaque accumulation, caries activity and salivary Streptococcus Mutans in a group of Saudi mother-child pairs. Materials and Methods: The study sample included 60 mother and child pairs selected on the basis of having high salivary streptococcus mutans levels. The study sample was randomly divided into experimental group (30 pairs) and control group(30 pairs). The experimental group was given xylitol treatment and the controls received fluoride varnish. Both groups were examined to assess caries, plaque and salivary streptococcus mutans levels. Xylitol treatment in the form of chewing gum for mothers and tablets for children was consumed three times/day for three months. All subjects received oral hygiene instructions, dietary counseling and restorative treatment. The results showed that the number of mothers and children with high streptococcus levels in the experimental group decreased to a statistically significant level at the end of the three month period, similarly, the control mothers showed the same trend. A statistically significant decrease in plaque scores was evident only among the children's experimental group. The caries level of children and mothers showed no statistically significant differences between the experimental and control groups. The factors which significantly affected the streptococcus mutans count in children after three months were the child's dmft at baseline the preventive method used and the mother' salivary streptococcus mutans level.

Keywords

Xylitol, Streptotcoccus mutans, caries, saliva, plaque, mother- child pairs

Cite and Share

Azza G Hanno,Najlaa M Alamoudi,Abdullah S Almushayt,Mohammed I Masoud,Heba J Sabbagh,Najat M Farsi. Effect of Xylitol on Dental Caries and Salivary Streptococcus Mutans Levels among a Group of Mother-Child Pairs. Journal of Clinical Pediatric Dentistry. 2012. 36(1);25-30.

References

1. Alamoudi N,Salako N, Masoud I. Prevalence and distribution of dental caries in the primary dentition in a cosmopolitan Saudi Population. Saudi Dent J, 7: 23–28, 1995.

2. Alamoudi N, Salako N, Masoud I. Caries experience of children aged 6-9 years in Jeddah, Saudi Arabia. Int J Ped Dent, 6: 101–105, 1996.

3. Loesche WJ. Role of Streptococcus mutans in human dental decay. Microbiol Rev, 50: 353–380, 1986.

4. Van Houte J, Jordan HV, Laraway R, Kent R, Soparkar PM, DePaola PF. Association of the microbial flora of dental plaque and saliva with human root-surface caries. J Dent Res, 69: 1463–1468, 1990.

5. Burt BA. The use of sorbitol- and xylitol- sweetened chewing gum in caries control. JADA, 137: 190–196, 2006.

6. Isokangas P, Tiekso J, Alanen P, Mäkinen KK. Long-term effect of xylitol chewing gum on dental caries. Community Dent Oral Epidemiol, 17: 200–203, 1989.

7. Isokangas P, Mäkinen KK, Tiekso J, Alanen P. Long-term effect of xylitol chewing gum on dental caries: a follow-up 5 years after termination of a prevention program. Caries Res, 27: 495–498, 1993.

8. Mäkinen KK, Bennett CA, Hujoel PP, et al. Xylitol chewing gums and dental caries rates: a 40-month cohort study. J Dent Res, 74: 1904–1913, 1995.

9. Mäkinen KK, Mäkinen PL, Pape HR Jr. et al. Stabilization of rampant caries: polyol gums and arrest of dentine caries in two long-term cohort studies in young subjects. Int Dent J, 45: 93–107, 1995.

10. Tanzer JM. Xylitol chewing gum and dental caries. Int Dent J, 45: 65–76, 1995.

11. Mäkinen KK, Chiego DJ, Allen P et al. Physical, chemical, and histological changes in dentin caries lesions of primary teeth induced by regular use of polyol chewing gums. Acta Odontol Scand, 56: 148–156, 1998.

12 Hujoel PP, Makinen KK, Benett CA, Isotupa KP, Isokangas PJ, Alanen P, Makinen PL. The optimum time to initiate habitual xylitol gumchewing for obtaining long term caries prevention. J Dent Res, 78: 797–803, 1999.

13. Söderling E, Alaraisanen L, Scheinin A, Mäkinen KK. Effect of xylitol and sorbitol on polysaccharide production by and adhesive properties of Streptococcus mutans. Caries Res, 21: 109–116, 1987.

14. Sato Y, Yamamoto Y, Kizaki H. Xylitol-induced elevated expression of the gbpC gene in a population of Streptococcus mutans cells. Eur J Oral Sci, 108: 538–545, 2000.

15 Bär A. Caries prevention with xylitol: a review of the scientific evidence. World Rev Nutr Diet, 55: 183–209, 1988.

16. Berkowitz RJ, Turner J, Green P. Maternal salivary levels of streptococcus mutans and primary oral infection of infants. Arch Oral Biol, 26: 147–149, 1981.

17. Caufield PW, Cutter GR, Dasanayake AP. Initial acquisition of mutans streptococci by infants: evidence for a discrete window of infectivity. J Dent Res, 72: 37–45, 1993.

18. Isokangas P,  Söderling K, Pienihäkkinen K, Alanen P. Occurrence of dental decay in children after maternal consumption of xylitol chewing gum, a follow-up from 0 to5 years of age. J Dent Res, 79: 1885–1889, 2000.

19. Alaluusua S, Renkonen OV. Streptococcus mutans establishment and dental caries experience in children from 2 to 4 years old. Scand J Dent Res. 91:453-457, 1983.

20. Kohler B, Andréen I, Johnson B. The effect of caries-preventive mea-sures in mothers on dental caries and the oral presence of the bacteria Streptococcus mutans and lactobacilli in their children. Arch Oral Biol, 29: 879–883, 1984.

21. Tenovuo J, Lehtonen OP, Aaltonen AS. Caries development in children in relation to the presence of mutans streptococci in dental plaque and of serum antibodies against whole cells and protein antigen I/II of Strp-tococcus mutans. Caries Res, 24: 59–64, 1990.

22. Söderling  E,  Isokangas  P,  Pienihäkkinen  K, Tenovuo  J.  Influence  of maternal xylitol consumption on the acquisition of mutans streptococci by infants. J Dent Res, 79: 882–887, 2000.

23. Söderling E, Isokangas P, Pienihäkkinen K, Tenovuo J,Alanen P. Influ-ence of maternal xylitol consumption on mother-child transmission of mutans streptococci: 6-year follow-up. Caries Res, 35: 173–177, 2001.

24. World Health Organization. Dental caries levels at 12 years (mimeo-graph of data from global data bank). Geneva: WHO 1987.

25. Greene C, Vermillion J. The simplified oral hygiene index. WHO 1964.

26. American Academy  of  Pediatrics.  Choking  prevention. Available  at: http://www.aap.org/pubed/ZZZSEN9YAC.htm&sub_cat=1

27. Isokangas P. Alanen P, Tiekso J, Makinen KK. Xylitol chewing gum in caries  prevention:  a  field  study  in  children.  J Am  Dent Assoc,  117: 315–320, 1988.

28. Makinen KK, Benett CA, Hujoel PP, Isokangas PJ, Isotupa KP, Rape HR, Makinen P-L: xylitol chewing gums and caries rates: a 40-months cohort study. J Dent Res, 74: 1904–1913, 1995.

29. Milgrom  P,  Ly  KA,  Roberts  MC,  Rothen  M,  Mueller  G, Yamaguchi DK. Mutans treptococci dose response to xylitol chewing gum. J Dent Res, 85: 177–181, 2006.

30. Ly KA, Milgrom P, Roberts MC, Yamaguchi DK, Rothen M, Mueller G.  Linear response of mutans streptococci to increasing frequency of xylitol  chewing  gum  use:  a  randomized  controlled  trial  [ISRCTN 43479664]. BMC Oral Health, 6: 6, 2006. 

31. Söderling E, Mäkinen KK, Chen CY, Pape HR Jr, Loesche W, Mäkinen PL. Long-term xylitol consumption and mutans streptococci in plaque and saliva. Caries Res, 25: 153–157, 1991.

32. Schaeken MJ, Keljens HM, van der Hoven JS. Effects of fluoride and chlorhexidine on the microflora of dental root surfaces and progression of root-surface caries. J Dent Res, 70: 150–153, 1991.

33. Campus  G,  Lumbau A,  Bachisio  SL.  Caries  experience  and  strepto-cocci and lactobaccili salivary levels in 6-8 year-old Sardinians Int J Paediatr Dent, 10: 306–312, 2000.

34. Larmas M, Scheinin A, Gehring F, Makinen KK. Turku sugar studies XX.  Microbiological findings and plaque index values in relation to 1-year use of xylitol chewing gum. Acta Odontol Scand, 34: 381–396, 1976.

35. Kandelman D, Gagnon G. A 24-month clinical study of the incidence and progression of dental caries in relation to consumption of chewing gum containing xylitol in school preventive programs. J Dental Res, 69: 1771–1775, 1990.

36. Hayes C. The effect of non-cariogenic sweeteners on the prevention of dental caries: a review of the evidence. J Dent Educ, 65: 1106–1109, 2001. 

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