Article Data

  • Views 606
  • Dowloads 106

Original Research

Open Access

Effect of Polyol Gums on Salivary S Mutans Levels

  • Subramaniam P1,*,
  • Suresh Babu P1

1Department of Pedodontics and Preventive Dentistry, the Oxford Dental College, Hospital and Research Centre

DOI: 10.17796/jcpd.36.2.3mr3843h52427k38 Vol.36,Issue 2,March 2012 pp.145-148

Published: 01 March 2012

*Corresponding Author(s): Subramaniam P E-mail:


The predominant sugar substitutes used in chewing gum are polyols which are low-caloric substances. The polyols most frequently used in chewing gums are sorbitol and xylitol. Aim:The present study assessed the effectiveness of xylitol and sorbitol chewing-gums on levels of S mutans in saliva. Method: The study group consisted of 30 normal and healthy males aged between 13-17 years. A pellet of gum (sorbitol or xylitol) was given to each participant after breakfast (8am), lunch (2pm) and dinner (8pm) for the study period of 3 months. On the first day of the study, baseline salivary samples were collected after breakfast from all participants and assessed for S mutans levels. At the end of 3 months, salivary samples were collected and processed in a similar manner. Conclusion: Salivary S mutans levels showed a significant reduction after the use of xylitol based chewing gum than with sorbitol based chewing gum.


xylitol, sorbitol, S mutans, polyols, chewing gums

Cite and Share

Subramaniam P,Suresh Babu P. Effect of Polyol Gums on Salivary S Mutans Levels. Journal of Clinical Pediatric Dentistry. 2012. 36(2);145-148.


1. Fontana M, Catt D, Eckert G, et al. Xylitol: Effects on the Acquisition of Cariogenic Species in Infants. Pediatr Dent, 31(3): 257–266, 2009.

2. Burt  B.  The  use  of  Sorbitol  and  xylitol  sweetened  chewing  gum  in caries control. JADA, 137: 190–196, 2006.

3. Ly K, Milgrom P, Rothen M. The potential of dental –protective chew-ing gum in oral health interventions. JADA, 139: 553–563, 2008.

4. Splieth C, Alkilzy M, Schmitt J, et al. Effect of xylitol and sorbital on plaque acidogenesis. Quint Inter, 40(4): 279–285, 2009.

5. Makenen KK, Soderling E, Isokangas P, et al. Oral biochemical status and  depression  of  streptococcus  mutans  in  children  during  24  to  36 month use of xylitol chewing gum. Caries Res, 23: 261–7, 1989.

6. Autio  JT.  Effect  of  xylitol  chewing  gum  on  salivary  streptococcus mutans  in  preschool  children. ASDC  J  Dent  Child,  69(1):  13,  81–6, 2002.

7. Makinen KK, Isotupa K, Makinen PL, et al. Six month polyol chewing gum programme in kindergarten age children: a feasibility study focus-ing on mutans streptococci and dental plaque. Inter Dent J, 55: 81–88, 2005.

8. Kakuta H, Iwami Y, HideakI M, et al. Xylitol inhibition of acid pro-duction and growth of mutans streptococci in the presence of various dietary  sugars  under  strictly  anaerobic  conditions.  Caries  Res,  37: 404–9, 2003.

9. Edgar  WM.  Sugar  Substitutes,  chewing  gum  and  dental  caries:  a review. Br Dent J, 184(1): 29–32, 1998.

10. Hayes C. The effect of non-cariogenic sweeteners on the prevention of dental caries: a review of the evidence. J Dent Educ, 65: 1106–9, 2001.

11. Gales MA, Nguyen TM. Sorbitol compared with xylitol in prevention of dental caries. Ann Pharmacother, 34(1): 98–100, 2000.

12. Makinen KK, Chen CY, Makinen PL, et al. Properties of whole saliva and  dental  plaque  in  relation  to  40-month  consumption  of  chewing gums containing xylitol, sorbitol or sucrose. Caries Res, 30(3): 180–8, 1996.

13. Makinen  KK,  Pemberton  D,  Makinen  PL,  et  al.  Polyol  –combinant saliva  stimulants  and  oral  health  in  Veterans  Affairs  patients:  an exploratory study. Spec Care Dentist, 16(3): 105–15,1996.

14. American  Academy  of  Pediatrics.  Parenting  corner  Q&A:  Choking prevention.  Accessed  March 27, 2008.

15. Ly KA, Milgrom P, Rothen M. Xylitol, sweeteners, and dental caries. Pediatr Dent, 28: 154–63, 2001.

16. Masalin K. Cries risk reducing effects of xylitol containing chewing gum and tablets in confectionery workers in Finland. Community Dent Health, 9: 3–10, 1992.

17. Makinen KK, Bennett CA, Hujoel PP, et al. Xylitol chewing gums and caries rate: A 40 month cohort study. J Dent Res, 74: 1904–13, 1995.

18. Akerblom  HK,  Koivukangas  T,  Puukka  R,  et  al.  The  tolerance  of increasing amounts of dietary xylitol in children. Int J Vitam Nutr Res, 22: 53–66, 1982.

19. Forster H Quadbeck R, Gottstein U. Metabolic tolerance to high doses of oral xylitol in human volunteers not previously adapted to xylitol. Int J Vitam Nutr Res, suppl 22:  67–88, 1982.

20. Autio JT, Courts FJ. Acceptance of the xylitol chewing gum regimen by  preschool  children  and  teachers  in  a  head  start  program:  a  pilot study. Pediatr Dent, 23(1): 71–74, 2001.

21. Hujoel PP, Makinen KK, Bennett CA, et al. The optimum time to initi-ate  habitual  xylitol  gum-chewing  for  obtaining  long  term  caries  pre-vention. J Dent Res, 78(3): 797–803, 1999.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

PubMed (MEDLINE) PubMed comprises more than 35 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 2.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time