Article Data

  • Views 593
  • Dowloads 120

Original Research

Open Access

Clinical and Radiographic Outcomes Of Pulpotomized Primary Molars Treated with White or Gray Mineral Trioxide Aggregate And Ferric Sulfate –Long Term Follow-Up

  • Frenkel G1
  • Kaufman A2
  • Ashkenazi M3,*,

1The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel-Aviv University, Tel-Aviv, Israel

2Department of Endodontics, School of Graduate Dentistry, Rambam Health Care Campus, and Faculty of Medicine, Technion, IIT, Haifa, Israel

3Senior Lecturer in Pediatric Dentistry, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel-Aviv University, Tel-Aviv, Israel. Currently, Pediatric Dentistry Dental Clinic, Petach-Tikva, Israel

DOI: 10.17796/jcpd.37.2.j3h27p624u163868 Vol.37,Issue 2,March 2013 pp.137-142

Published: 01 March 2013

*Corresponding Author(s): Ashkenazi M E-mail:


Aim: To compare the long term clinical and radiographic outcomes of pulpotomies in primary molars per-formed with white or gray Mineral Trioxide Aggregate (MTA) in combination with ferric sulfate (FS), when one package of MTA is used for multiple treatments. Design: Sixty eight children with 86 vital carious primary molars underwent pulpotomy with FS, and grey or white MTA. One package of MTA was used for 7-8 treatments. Clinical and radiographic evaluation was performed before and 6 to 47 months after treatment. Results: Success rates were similar for pulpotomies performed with white (60-teeth) and grey MTA (16 teeth) (p>0.05), and for those performed with the addition of FS to white or gray MTA when one package of MTA was used for multiple pulpotomies compared to one package of MTA alone. Conclusion: Gray and white MTA in conjunction with FS induce comparable clinical and radiographic success rate. The use of one package of MTA for multiple pulpotomies, combined with FS, is a cost-effective treatment.


MTA, pulpotomy, ferric sulfate, children

Cite and Share

Frenkel G,Kaufman A,Ashkenazi M. Clinical and Radiographic Outcomes Of Pulpotomized Primary Molars Treated with White or Gray Mineral Trioxide Aggregate And Ferric Sulfate –Long Term Follow-Up. Journal of Clinical Pediatric Dentistry. 2013. 37(2);137-142.


1. Primosch RE, Glomb TA, Jerrell RG. Primary tooth pulp therapy as taught in predoctoral pediatric dental programs in the United States. Pediatr Dent;19:118-122. 1997.

2. Sun HW, Feigal RJ, Messer HH. Cytotoxicity of glutaraldehyde and formaldehydein relation to time of exposure and concentration. Pediatr Dent;12:303-307. 1990.

3. Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggre-gate. J Endod ;25:197-205.1999.

4. Torabinejad M, Hong CU, McDonald F, Pitt Ford TR. Physical and chem-ical properties of a new root-end filling material. J Endod;21:349-353. 1995.

5. Koh ET, Torabinejad M, Pitt Ford TR, Brady K, McDonald F. Mineral trioxide aggregate stimulates a biological response in human osteoblasts. J Biomed Mater Res; 5;37:432-439. 1997.

6. Tziafas D, Pantelidou O, Alvanou A, Belibasakis G, Papadimitriou S. The dentinogenic effect of mineral trioxide aggregate (MTA) in short-term capping experiments. Int Endod J;35:245-254. 2002.

7. Ng FK, Messer LB. Mineral trioxide aggregate as a pulpotomy medica-ment: an evidence-based assessment. Eur Arch Paediatr Dent; 9:58-73. 2008.

8. Maroto M, Barbería E, Planells P, García Godoy F. Dentin bridge formation after mineral trioxide aggregate (MTA) pulpotomies in primary teeth. Am J Dent.;18:151-154. 2005.

9. Ford TR, Torabinejad M, Abedi HR, Bakland LK, Kariyawasam SP. Using mineral trioxide aggregate as a pulp-capping material. J Am Dent Assoc;127:1491-1494. 1996.

10. Sonmez D, Sari S, Cetinbaş TA. Comparison of four pulpotomy techniques in primary molars: a long-term follow-up. J Endod;34:950-955. 2008.

11. Farsi N, Alamoudi N, Balto K, Mushayt A. Success of mineral trioxide aggregate in pulpotomized primary molars. J Clin Pediatr Dent;29:307- 311. 2005.

12. Agamy HA, Bakry NS, Mounir MM, Avery DR. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth. Pediatr Dent; 26:302-309. 2004.

13. Pruhs RJ, Olen GA, Sharma PS. Relationship between formocresol pulpo-tomies on primary teeth and enamel defects on their permanent successors. J Am Dent Assoc;94:698-700. 1977.

14. Peng L, Ye L, Guo X, Tan H, Zhou X, Wang C, Li R. Evaluation of formo-cresol versus ferric sulphate primary molar pulpotomy: a systematic review and meta-analysis. Int Endod J;40:751-757. 2007.

15. Ashkenazi M, Blumer S, Eli I. Effect of computerized delivery intraliga-mental injection in primary molars on their corresponding permanent tooth buds. Int J Paediatr Dent;20:270-275. 2010.

16. Angelus. MTA Angelus: cimento reparador. Londrina: Angelus.

17. Koulaouzidou EA, Economides N, Beltes P, Geromichalos G, Papazisis K. In vitro evaluation of the cytotoxicity of ProRoot MTA and MTA Angelus. J Oral Sci;50:397-402. 2008.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

PubMed (MEDLINE) PubMed comprises more than 35 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 2.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time