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Original Research

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Evaluation of Salivary Sialic Acid Levels in Acute Lymphoblastic Leukemic Children and Its Correlation with Dental Caries Experience

  • Joshi S1,*,
  • Hegde A M2
  • Rai K2
  • Shetty S2

1Department of Pedodontics, Rural Dental College, Loni, Dist. Ahmednagar, Maharashtra, India

2Department of Pedodontics and Preventive Children Dentistry, A.B Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.

DOI: 10.17796/jcpd.37.3.7808167071871754 Vol.37,Issue 3,May 2013 pp.309-313

Published: 01 May 2013

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Abstract

The aim of present study was to evaluate the salivary sialic acid levels in Acute Lymphoblastic Leukemic (ALL) children and to correlate it with dental caries experience. Method- A total of 120 children aged 4-10yrs were divided into 4 groups of 30 each. Dental caries experience was recorded followed by un-stimulated saliva collection. Results- The mean salivary sialic acid levels of the study group were much higher when compared with the control group, which was statistically significant. A linear relationship between salivary sialic acid levels and dental caries in leukemic children was observed. Conclusion - The findings of our study conclude that salivary sialic acid levels may have a potent activity in dental caries process and can be used as a useful marker in cancer.

Keywords

Sialic Acid, Saliva, Dental caries, Acute Lymphoblastic Leukemia(ALL).

Cite and Share

Joshi S,Hegde A M,Rai K,Shetty S. Evaluation of Salivary Sialic Acid Levels in Acute Lymphoblastic Leukemic Children and Its Correlation with Dental Caries Experience . Journal of Clinical Pediatric Dentistry. 2013. 37(3);309-313.

URL:

https://www.jocpd.com/articles/10.17796/jcpd.37.3.7808167071871754

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