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Original Research

Open Access

Initial Experience with Dexmedetomidine for Dental Sedation in Children

  • Hyo Sun Kim1
  • Jung-Wook Kim2
  • Ki-Taeg Jang2
  • Sang-Hoon Lee2
  • Chong-Chul Kim2
  • Teo Jeon Shin2,*,

1Department of Pediatric Dentistry, Seoul National University Hospital , Seoul, Republic of Korea

2Department of Pediatric Dentistry, and Dental Research Institute, College of Dentistry, Seoul National University, Seoul, Republic of Korea

3,

DOI: 10.17796/jcpd.38.1.w86t8k7r51k72617 Vol.38,Issue 1,January 2014 pp.79-82

Published: 01 January 2014

*Corresponding Author(s): Teo Jeon Shin E-mail: snmc94@snu.ac.kr

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Abstract

Sedation of uncooperative children for dental treatment is difficult since treatment is mainly carried out inside the oral cavity. Dexmedetomidine (DEX), recently introduced into clinical practice, has little influence on respiratory system even at high doses. We present cases of patients who underwent dental treatment under sedation using DEX infusion. DEX at a dose of 1 μg/kg was administered over 10 min after intravenous cannulation. DEX was infused to maintain sedation level within the range of the Observer's Assessment of Alertness and Sedation (OAA/S) scale 3- 4 throughout dental treatments. They were successfully treated under DEX sedation without any complications. Their uncooperative behaviors were successfully managed under DEX sedation.

Keywords

Dexmedetomidine, Deep Sedation, Pediatric Dentistry

Cite and Share

Hyo Sun Kim,Jung-Wook Kim,Ki-Taeg Jang,Sang-Hoon Lee,Chong-Chul Kim,Teo Jeon Shin. Initial Experience with Dexmedetomidine for Dental Sedation in Children. Journal of Clinical Pediatric Dentistry. 2014. 38(1);79-82.

URL:

https://www.jocpd.com/articles/10.17796/jcpd.38.1.w86t8k7r51k72617

References

1. Berkenbosch JW, Wankum PC, Tobias JD. Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children. Pediatr Crit Care Med, 6: 435-439, 2005.

2. Tobias JD, Berkenbosch JW. Initial experience with dexmedetomidine in paediatric-aged patients. Paediatr Anaesth, 12: 171-175, 2002.

3. Heard CMB, Joshi P, Johnson K. Dexmedetomidine for pediatric MRI sedation: a review of a series of cases. Paediatr Anaesth, 17: 888-892, 2007.

4. McMorrow SP, Abramo TJ. Dexmedetomidine Sedation: Uses in Pediatric Procedural Sedation Outside the Operating Room. Pediatr Emerg Care, 28: 292- 296, 2012.

5. Mason KP, Zgleszewski SE, Dearden JL, Dumont RS, Pirich MA, Stark CD, D’Angelo P, Macpherson S, Fontaine PJ, Connor L, Zurakowski D. Dexmedetomidine for Pediatric Sedation for Computed Tomography Imaging Studies. Anesth Analg, 103: 57-62, 2006.

6. Koroglu A, Demirbilek S, Teksan H, Sagir O, But AK, Ersoy MO. Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: preliminary results. Br J Anaesth, 94: 821-4, 2005.

7. Taniyama K, Oda H, Okawa K, Himeno K, Shikanai K, Shibutani T. Psychosedation With Dexmedetomidine Hydrochloride During Minor Oral Surgery. Anesth Prog, 56:75-80, 2009.

8. Kawaai H, Tomita S, Nakaike Y, Ganzberg S, Yamazaki S. Intravenous sedation for implant surgery: Midazolam, butorphanol and dexmedeto-midine versus midazolam, butorphanol and propofol. J Oral Implantol, in press, 2011.

9. Panzer O, Moitra V, Sladen RN. Pharmacology of Sedative-Analgesic Agents: Dexmedetomidine, Remifentanil, Ketamine, Volatile Anesthetics, and the Role of Peripheral Mu Antagonists. Crit Care Clin, 25: 451-469, 2009.

10. Hsu Y-W, Cortinez LI, Robertson KM, Keifer JC, Sum-Ping ST, Moretti EW, Young CC, Wright DR, Macleod DB, Somma J. Dexmedetomidine Pharmacodynamics: Part I: Crossover Comparison of the Respiratory Effects of Dexmedetomidine and Remifentanil in Healthy Volunteers. Anesthesiology, 101: 1066-1076, 2004.

11. Munro HM, Tirotta CF, Felix DE, Lagueruela RG, Madril DR, Zahn EM, Nykanen DG. Initial experience with dexmedetomidine for diagnostic and interventional cardiac catheterization in children Paediatr Anaesth, 17: 109- 112, 2007.

12. Coté CJ, Notterman DA, Karl HW, Weinberg JA, McCloskey C. Adverse Sedation Events in Pediatrics: A Critical Incident Analysis of Contributing Factors. Pediatrics, 105: 805-814, 2000.

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