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Open AccessMatrix Metalloproteinases (Mmp) in Restorative Dentistry and Endodontics
Matrix Metalloproteinases (Mmp) in Restorative Dentistry and Endodontics
1Tamil Nadu, India
DOI: 10.17796/jcpd.39.1.x452446251r1q428 Vol.39,Issue 1,January 2015 pp.57-59
Published: 01 January 2015
*Corresponding Author(s): Neelakantan P E-mail: prasanna_neelakantan@yahoo.com
Abstract
Matrix metalloproteinases (MMPs) seem to play a dual role in dentistry. While several MMPs have an important role to play in developmental defects of teeth and in caries, some MMPs also seem to have a defensive role. The main organic component of tooth structure is collagen and MMPs that degrade collagen and the extra cellular matrix have been implicated in progression of dental caries. MMPs have also been shown to be active in pulpitis and studies have shown that they can be used as diagnostic markers of pulpal inflammation. This paper reviews the role of MMPs in restorative dentistry and endodontics.
Keywords
Matrix metalloproteinase; collagen; dental caries; dentinogenesis; pulpitis; diagnostic marker
Cite and Share
Sambandam V,Neelakantan P. Matrix Metalloproteinases (Mmp) in Restorative Dentistry and Endodontics. Journal of Clinical Pediatric Dentistry. 2015. 39(1);57-59.
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