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A rare maxillofacial manifestation of acute lymphoblastic leukemia in a 9-year-old child

  • Saubhik Dasukil1
  • Akshay Lahoti2
  • Ashok Kumar Jena1,*,
  • Amit Kumar Adhya3
  • Prabodha Kumar Das2

1Department of Dentistry, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India

2Department of Medical Oncology/Hematology, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India

3Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India

DOI: 10.22514/jocpd.2022.014 Vol.46,Issue 5,September 2022 pp.98-101

Published: 01 September 2022

*Corresponding Author(s): Ashok Kumar Jena E-mail: dent_ashok@aiimsbhubaneswar.edu.in

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Abstract

Acute lymphoblastic leukemia (ALL) is considered as the most common malignant neoplasm of childhood and the frequent cause of death from cancer before 20-years of age. The facial swelling mimicking a maxillofacial tumor is rarely associated with ALL. Clinicians should be aware of such rare manifestation of ALL. We present a case with an atypical mass in the facial region secondary to ALL, which resulted in diagnostic dilemma. Reports of such atypical swelling in patients with ALL are occasional. The swelling was aggressive and the disease had a fulminant course.


Keywords

Children; Maxillary swelling; Acute lymphoblastic leukemia; B-Cell lymphoblastic lymphoma


Cite and Share

Saubhik Dasukil,Akshay Lahoti,Ashok Kumar Jena,Amit Kumar Adhya,Prabodha Kumar Das. A rare maxillofacial manifestation of acute lymphoblastic leukemia in a 9-year-old child. Journal of Clinical Pediatric Dentistry. 2022. 46(5);98-101.

URL:

https://www.jocpd.com/articles/10.22514/jocpd.2022.014

References

1. Pieters R, Carroll WL. Biology and treatment of acute lymphoblastic leukemia. Hematology/Oncology Clinics of North America. 2010; 24: 1–18.

2. Sánchez-Romero C, Pontes HAR, Pontes FSC, Rocha AC, Carlos R, Rendón JC, et al. Acute lymphoblastic leuke-mia/lymphoma of the oral and maxillofacial region. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2018; 126: 152–164.

3. Hou GL, Huang JS, Tsai CC. Analysis of oral manifestations of leukemia: a retrospective study. Oral Diseases. 1997; 3: 31–38.

4. White GE. Oral manifestations of leukemia in children. Oral Surgery, Oral Medicine, Oral Pathology. 1970; 29: 420-427.

5. Dalirsani Z, Ghazi A. T-cell lymphoblastic lymphoma in the maxilla and mandible of a child: a rare case report. Journal of Clini-cal and Diagnostic Research. 2015; 9: ZD22–ZD24.

6. Cavalcante AS, Anbinder AL, Pontes EM, Carvalho YR. B-cell lymphoblastic lymphoma in the maxilla of a child: a rare case report. International Journal of Oral and Maxillofacial Surgery. 2009; 38: 1326–1330.

7. Karimi M, Eshghi P. Unusual lymphoblastic leukemia/lymphoma in eastern Iran. The Indian Journal of Pediatrics. 2006; 73: 619–622.

8. Brito AC, Capistrano HM, Torres ML, Ramos G, Viana MB, Oliveira BMD. Isolated relapse in the oral cavity of a child with t- lineage acute lymphoblastic leukemia. Brazilian Dental Journal. 2012; 23: 711–715.

9. Fallahinejad Ghajari M, Moshref M, Taghipour E. Maxilla unilateral swelling as the first diagnostic symptom of acute lymphoblastic leukemia relapse: a case report. Journal of Dentistry. 2011; 8: 44–47.

10. Boccara O, Laloum-Grynberg E, Jeudy G, Aubriot-Lorton M, Vabres P, de Prost Y, et al. Cutaneous B-cell lympho-blastic lymphoma in children: a rare diagnosis. Journal of the American Academy of Dermatology. 2012; 66: 51–57.

11. Jaffe ES, Barr PM, Smith SM. Understanding the new who classification of lymphoid malignancies: why it’s important and how it will affect practice. American Society of Clinical Oncology Educational Book. 2017; 99: 535–546.

12. Ducassou S, Ferlay C, Bergeron C, Girard S, Laureys G, Pacquement H, et al. Clinical presentation, evolution, and prognosis of precursor B-cell lymphoblastic lymphoma in trials LMT96, EORTC 58881, and EORTC 58951. British Journal of Haematology. 2011; 152: 441–451.

13. Rosolen A, Perkins SL, Pinkerton CR, Guillerman RP, Sandlund JT, Patte C, et al. Revised international pediatric non-hodgkin lymphoma staging system. Journal of Clinical Oncology. 2015; 33: 2112–2118.


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