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Central granular cell odontogenic tumor of mandible in a child

  • Saravanan Lakshmanan1
  • Babu Lal1
  • Rudra Deo Kumar1
  • Deepika Mishra2
  • Ongkila Bhutia1,3,*,

1Department of Oral and Maxillofacial Surgery, All India Institute of Medical Sciences, New Delhi, India

2Department of Oral Pathology and Microbiology, All India Institute of Medical Sciences, New Delhi, India

3Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India

DOI: 10.22514/jocpd.2022.027 Vol.46,Issue 6,November 2022 pp.54-57

Published: 01 November 2022

*Corresponding Author(s): Ongkila Bhutia E-mail:


Central granular cell odontogenic tumor (CGCOT) is sporadic benign odontogenic tumor and it especially occurs in women older than 50 years of age. Radiologically it manifests as unilocular to the multilocular radiolucency with sometimes mixed densities. Histopathology displays sheets and islands of large eosinophilic cells with abundant granular cytoplasm, however few cases exhibit inadequate epithelium, thus creating a diagnostic confusion. Though, resection is advocated by some surgeons, however because of the non-aggressive biological behaviour, enucleation or curettage is the treatment of choice for this lesion. Till now only 39 cases have been reported in the past six decades. We are reporting the first case of CGCOT occurring in the youngest age of eleven-year-old patient with massive size of 11 × 7 × 6 cm. This would add CGCOT as a differential diagnosis in the bony lesions of younger individuals. In addition, the importance of immunohistochemistry studies in cases with scarce odontogenic epithelium and the potential role of Carnoy’s solution in the management of this rare tumor in this age group was emphasized.


Odontogenic tumor; Children; Granular cell tumor; Pediatric tumor; Vimentin

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Saravanan Lakshmanan,Babu Lal,Rudra Deo Kumar,Deepika Mishra,Ongkila Bhutia. Central granular cell odontogenic tumor of mandible in a child. Journal of Clinical Pediatric Dentistry. 2022. 46(6);54-57.


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