Article Data

  • Views 1451
  • Dowloads 260

Case Reports

Open Access

Regional odontodysplasia on the left side of the mandible: report of an unusual case

  • Yuezhi Ji1
  • Yunyi Wang1
  • Shuhui Huang1
  • Feng Zhang1,*,

1Department of Stomatology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 310051, Hangzhou, Zhejiang, China

DOI: 10.22514/jocpd.2023.068 Vol.47,Issue 5,September 2023 pp.176-180

Submitted: 21 September 2022 Accepted: 24 November 2022

Published: 03 September 2023

*Corresponding Author(s): Feng Zhang E-mail:


Regional odontodysplasia (RO) is a rare developmental abnormality of epithelial and mesenchymal dental tissues. Due to its poorly understood etiology, assessing and discussing related clinical cases of this dental anomaly is crucial to guide professionals in improving its treatment and outcomes. This article aimed to report the case of a 9-year-old male patient who presented to our department with the main complaint of absent eruption of permanent left mandibular quadrant teeth. This is the first case reported in China from a patient with multiple cutaneous nevi on the face and neck, and based on the retrieved clinical and radiographic features, we described and discussed the treatment and etiology of RO.


Regional odontodysplasia; Ghost teeth; Etiology

Cite and Share

Yuezhi Ji,Yunyi Wang,Shuhui Huang,Feng Zhang. Regional odontodysplasia on the left side of the mandible: report of an unusual case. Journal of Clinical Pediatric Dentistry. 2023. 47(5);176-180.


[1] Tervonen SA, Stratmann U, Mokrys K, Reichart PA. Regional odontodys-plasia: a review of the literature and report of four cases. Clinical Oral Investigations. 2004; 8: 45–51.

[2] de Sá Cavalcante D, Fonteles C S, Ribeiro T R, Kurita L M, Pimenta A V M, Sr Carvalho F, et al. Mandibular regional odontodysplasia in an 8-year-old boy showing teeth disorders, gubernaculum tracts, and altered bone fractal pattern. International Journal of Clinical Pediatric Dentistry. 2018; 11: 128–134.

[3] Alotaibi O, Alotaibi G, Alfawaz N. Regional odontodysplasia: an analysis of 161 cases from 1953 to 2017. Saudi Dental Journal. 2019; 31: 306–310.

[4] Nijakowski K, Woś P, Surdacka A. Regional odontodysplasia: a systematic review of case reports. International Journal of Environmental Research and Public Health. 2022; 19: 1683.

[5] Ozer L, Cetiner S, Ersoy E. Regional odontodysplasia: report of a case. Journal of Clinical Pediatric Dentistry. 2004; 29: 45–48.

[6] Hamdan M A, Sawair F A, Rajab L D, Hamdan A M, Al-Omari I K. Regional odontodysplasia: a review of the literature and report of a case. International Journal of Paediatric Dentistry. 2004; 14: 363–370.

[7] Damasceno J X, Couto J L, Alves K S, Chaves C M, Jr., Costa F W, Pimenta Ade M, et al. Generalized odontodysplasia in a 5-year-old patient with Hallermann-Streiff syndrome: clinical aspects, cone beam computed tomography findings, and conservative clinical approach. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology. 2014; 118: e58–64.

[8] Koskinen S, Keski-Filppula R, Alapulli H, Nieminen P, Anttonen V. Familial oligodontia and regional odontodysplasia associated with a PAX9 initiation codon mutation. Clinical Oral Investigations. 2019; 23: 4107–4111.

[9] Magalhães AC, Pessan JP, Cunha RF, Delbem AC. Regional odontodysplasia: case report. Journal of Applied Oral Science: Revista FOB. 2007; 15: 465–469.

[10] Ramakrishnan M. Odontodysplasia involving single tooth: a rare entity. SRM Journal of Research in Dental Sciences. 2014; 5: 140–142.

[11] Rosa MC, Marcelino GA, Belchior RS, Souza AP, Parizotto SC. Regional odontodysplasia: report of case. Journal of Clinical Pediatric Dentistry. 2006; 30: 333–336.

[12] Gündüz K, Zengin Z, Celenk P, Ozden B, Kurt M, Gunhan O. Regional odontodysplasia of the deciduous and permanent teeth associated with eruption disorders: a case report. Medicina Oral, Patologia Oral y Cirugia Bucal. 2008; 13: E563–566.

[13] Silva Cunha JL, Barboza Santana AV, Alves da Mota Santana L, Meneses Santos D, de Souza Amorim K, Maciel de Almeida Souza L, et al. Regional odontodysplasia affecting the maxilla. Head and Neck Pathology. 2020; 14: 224–229.

[14] Bowden E, Carroll C, Gill M, Llewelyn R. Cervicofacial infection in a 3-year-old child with regional odontodysplasia: a case report and literature review. Journal of Oral and Maxillofacial Pathology. 2018; 22: S117–S120.

[15] Mathew A, Dauravu LM, Reddy SN, Kumar KR, Venkataramana V. Ghost teeth: regional odontodysplasia of maxillary first molar associated with eruption disorders in a 10-year-old girl. Journal of Pharmacy and Bioallied Sciences. 2015; 7: S800–803.

[16] Koruyucu M, Yaman D, Seymen F, Demirel K, Gençay K. Management of regional odontodysplasia: a 10-year-follow-up case report and literature review. European Oral Research. 2018; 52: 111–116.

[17] Rashidian A, Afsharian Zadeh M, Azarshab M, Zarrabian T. Regional odontodysplasia: report of a case. Journal of Dentistry. 2013; 14: 197–200.

[18] Kappadi D, Ramasetty PA, Rai KK, Rahim AM. Regional odontodysplasia: an unusual case report. Journal of Oral and Maxillofacial Pathology. 2009; 13: 62–66.

[19] Canela AH, Rezende KM, Benitez M, Bönecker M. Early diagnosis of regional odontodysplasia in an infant. Journal of Craniofacial Surgery. 2012; 23: e134–136.

[20] Rosa MC, Marcelino GA, Belchior RS, Souza AP, Parizotto SC. Regional odontodysplasia: report of case. Journal of Clinical Pediatric Dentistry. 2006; 30: 333–336.

[21] Babu N S, Smriti R J, Pratima D B. Regional odontodysplasia: report of an unusual case involving mandibular arch. Contemporary Clinical Dentistry. 2015; 6: 237–239.

[22] Iizawa F, Kinjoh N, Taguchi Y. Regional odontodysplasia: long-term observation of a case on the mandibular left side. Pediatric Dental Journal. 2010; 20: 103–109.

[23] Matsuyama J, Tanaka R, Iizawa F, Sano T, Kinoshita-Kawano S, Hayashi-Sakai S, et al. Clinical and radiographic findings and usefulness of computed tomographic assessment in two children with regional odontodysplasia. Case Reports in Dentistry. 2014; 2014: 764393.

[24] Crawford P J, Aldred M, Bloch-Zupan A. Amelogenesis imperfecta. Orphanet Journal of Rare Diseases. 2007; 2: 17.

[25] Carlos R, Contreras-Vidaurre E, Almeida OP, Silva KR, Abrahão PG, Miranda A M, et al. Regional odontodysplasia: morphological, ultrastructural, and immunohistochemical features of the affected teeth, connective tissue, and odontogenic remnants. Journal of Dentistry for Children. 2008; 75: 144–150.

[26] Ziegler S, Neukam FW. Regional odontodysplasia: orthodontic treatment and transplantation of premolars. American Journal of Orthodontics and Dentofacial Orthopedics. 2012; 142: 710–719.

[27] Abdel-Kader MA, Abdelazeem AF, Ahmed NEB, Khalil YM, Mostafa MI. Oral rehabilitation of a case with regional odontodysplasia using a regenerative approach—a case report and a review of literature. Special Care in Dentistry. 2019; 39: 330–339.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 2.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time