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Assessment of severity and mineral composition of saliva in schoolchildren with molar-incisor hypomineralization (MIH)

  • Narmin Ismayilova1
  • Ozge Erken Gungor1,*,
  • Huseyin Karayilmaz1

1Department of Pediatric Dentistry, Faculty of Dentistry, Akdeniz University, 07058 Antalya, Turkey

DOI: 10.22514/jocpd.2024.024 Vol.48,Issue 3,May 2024 pp.86-93

Submitted: 11 August 2023 Accepted: 27 September 2023

Published: 03 May 2024

*Corresponding Author(s): Ozge Erken Gungor E-mail:


The aim of the study was to evaluate the severity of molar incisor hypomineralisation (MIH), related oral health and investigate salivary mineral composition. The study was conducted with 50 participants aged between 6–15 years who were effected with MIH and 50 without MIH. The International Caries Detection and Assessment System (ICDAS) scores, Decayed, Missing, Filled Teeth/Surface (DMFT/S), dft/s and gingival/plaque indices were evaluated. The pH, flow rate, buffering capacity and mineral composition of saliva was measured. “Student t” test, one-way analysis of variance in repeated measurements of groups, and Tukey multiplex in subgroup comparisons was used. Kruskal-Wallis, Mann-Whitney U, Wilcoxon and chi-square tests were used to analyze qualitative data and compare groups. A total of 100 children (57 females 43 males, mean age 10.12 ± 1.85) participated in the study. There was no difference between ICDAS, DMFT/S scores, but dft/s index values were statistically significant (p = 0.001). The simplified oral hygiene index of MIH patients were statistically higher, but no significant differences were found in modified gingival indices (p = 0.52). Although the salivary pH and flow rate of the patients in the study group were lower, the buffering capacity was higher than those in the control group, but no significant difference was observed (p = 0.64). The mean values of phosphorus, carbon and calcium content in the saliva samples of MIH patients were higher than those of patients without MIH, and this difference was low for phosphorus (p = 0.76) and carbon (p = 0.74), but significantly higher for calcium. To the best of our knowledge, this is the first study to evaluate the association between calcium, phosphate and carbon levels in saliva of children with MIH. The significantly high amount of calcium in the saliva of patients with MIH suggests that further investigations are needed.


Molar-incisor hypomineralisation; Saliva; Calcium; Phosphate; Carbon

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Narmin Ismayilova,Ozge Erken Gungor,Huseyin Karayilmaz. Assessment of severity and mineral composition of saliva in schoolchildren with molar-incisor hypomineralization (MIH). Journal of Clinical Pediatric Dentistry. 2024. 48(3);86-93.


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