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Original Research

Open Access

Management of severity lesions of hypomineralized molars (MIH) with different treatment alternatives: 9-month results of a clinical trial

  • Mine Ozsoy1
  • Ozge Erken Gungor1,*,

1Department of Pediatric Dentistry Antalya, Akdeniz University Faculty of Dentistry, 07058 Antalya, Turkey

DOI: 10.22514/jocpd.2024.061 Vol.48,Issue 3,May 2024 pp.68-75

Submitted: 11 August 2023 Accepted: 12 September 2023

Published: 03 May 2024

*Corresponding Author(s): Ozge Erken Gungor E-mail:


The aim of this study was to evaluate the 9-month clinical performance of different materials and treatment procedures in teeth with MIH in children, and to evaluate the effectiveness of Papacarie gel as a deproteinization agent. The study included 90 children (aged 8–15) who had 189 first permanent molars with MIH were restored randomly with 4 different materials/methods. Equia Forte HT (GC, Tokyo, Japan) was used in Group 1; In Group 2, G-eanial composite (GC, Tokyo, Japan) was used with a Fuji IX (GC, Tokyo, Japan) base; In Group 3 and Group 4, EverX Posterior (GC, Tokyo, Japan) base and G-eanial composite (GC, Tokyo, Japan) were used. In group 4, deproteinization was performed with Papacarie Duo gel (F&A, Sao Paulo, Brazil). The restorations were evaluated at 3-month intervals for 9 months using modified United States Public Health Service (USPHS) criteria. The overall recall rate was 94.1% for every 3-month clinical evaluation over 9 months. A total of 9 restorations were unsuccessful. Surface roughness of Group 1 was statistically different from all other groups in all control periods (p < 0.05). Marginal adaptation of Group 2 was found to be significantly different from Groups 3 and 4 at the both of 6th and 9th month controls. There was no significant difference between the groups in terms of retention, color match, marginal discoloration and secondary caries in all control months. Restoration of MIH with Equia Forte HT is almost as successful as composites. The use of dentin replacement materials instead of glass ionomer cements as a base in composite restorations shows better results. Papacarie deproteinization showed similar success with other composite groups. This study was the first clinical study in which Papacarie was used for deproteinization in teeth with MIH and will thus contribute to the literature.


Equia Forte HT; EverX posterior; Deproteinization; MIH; Papacarie

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Mine Ozsoy,Ozge Erken Gungor. Management of severity lesions of hypomineralized molars (MIH) with different treatment alternatives: 9-month results of a clinical trial. Journal of Clinical Pediatric Dentistry. 2024. 48(3);68-75.


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