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Original Research

Open Access

Green light exposure in children with autism spectrum disorder: a pilot study

  • Caroline M. Sawicki1,*,
  • Paz Duran2,3
  • Sara Hestehave4
  • Rajesh Khanna2,3,5
  • Spencer D. Wade6,7

1Division of Pediatric and Public Health, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC 27517, USA

2Pain Research Center, New York University, New York, NY 10010, USA

3Department of Molecular Pathobiology, New York University, New York, NY 10010, USA

4Department of Experimental Medicine, University of Copenhagen, 2200 Copenhagen N, Denmark

5Department of Pharmacology & Therapeutics, University of Florida College of Medicine, Gainesville, FL 32610, USA

6Department of Oral and Maxillofacial Surgery, College of Dentistry, New York University, New York, NY 10010, USA

7Oral Health Center for People with Disabilities, College of Dentistry, New York University, New York, NY 10010, USA

DOI: 10.22514/jocpd.2024.083 Vol.48,Issue 4,July 2024 pp.99-107

Submitted: 11 January 2024 Accepted: 20 March 2024

Published: 03 July 2024

*Corresponding Author(s): Caroline M. Sawicki E-mail: caroline_sawicki@unc.edu

Abstract

Children with autism spectrum disorder (ASD) are frequently afflicted with sensory processing difficulties, which often impact their ability to cooperate with dental treatment. The objective of this pilot study was to determine the effects of green light exposure on behavior, pain, distress and anxiety in pediatric patients with ASD undergoing a dental prophylaxis. Twelve children diagnosed with ASD, aged 6–17 years, requiring a dental prophylaxis participated in this study. Participants completed two dental prophylaxes, three months apart, one in a standard white light-exposed dental operatory and one in a green light-exposed dental operatory. Behavioral cooperation, pain intensity, physiological stress and anxiety were assessed in all patients. The Wilcoxon matched-pairs signed rank test was used to estimate differences in measured outcomes according to the experimental condition. There was a trend towards reduced uncooperative behavior when children received a dental prophylaxis in the green light-exposed operatory (p = 0.06). Similar levels of heart rate variability (p = 0.41), salivary alpha amylase (p = 0.19), and salivary cortisol (p = 0.67) were observed at the start and end of each visit in both conditions. Green light exposure had no significant effect on pain intensity (p = 0.17) or behavioral anxiety (p = 0.31). These findings suggest a preliminary positive benefit of green light exposure on behavioral outcomes in pediatric patients with ASD and warrants a further, large-scale clinical trial.


Keywords

Autism spectrum disorder; Green light; Anxiety; Pain; Stress


Cite and Share

Caroline M. Sawicki,Paz Duran,Sara Hestehave,Rajesh Khanna,Spencer D. Wade. Green light exposure in children with autism spectrum disorder: a pilot study. Journal of Clinical Pediatric Dentistry. 2024. 48(4);99-107.

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