Clinical anesthetic effect of intraseptal injection combined with periodontal ligament injection in treatment of deep caries in mandibular deciduous molars

Background: There was no comfortable and effective local anesthesia for treating deep caries in mandibular deciduous molars. Methods: This study had two parts: pre-experiment and main-experiment. In pre-experiment, 40 children with deep caries in mandibular deciduous molars randomly received local anesthesia by PL injection (PL group) or IS injection (IS group) before the treatment. In main-experiment, another 60 children received local anesthesia by PL injection (PL2 group) or IS combined with PL injection (IS + PL group). In both the pre-experiment and main-experiment, children separately gave the scores of injection and treatment pain through Wong-Baker FACE® Pain Rating Scale (WB). Results: The injection pain in PL and IS groups were 5.10 ± 2.29 and 2.30 ± 0.73 (p < 0.001). The anesthesia success rates for PL and IS groups were 90% and 60% (p < 0.01). The injection pain in PL2 and IS + PL groups were 5.67 ± 2.11 and 2.73 ± 0.98 (p < 0.001). The anesthetic success rates for PL2 and IS+ PL groups were 83.3% and 86.7% (p > 0.05). The treatment pain in PL2 and IS + PL groups were 1.68 ± 1.49 and 1.85 ± 1.48 (p > 0.05). Conclusions: The anesthetic effect of IS combined with PL injection, and PL injection alone were similar, however IS combined with PL injection had lower pain sensation during the anesthesia, which might be conducive in the oral treatment of children. Clinical Trial Registration: The registration number of the UK’s Clinical Study Registry is ISRCTN30082181.

Intraseptal injection; Periodontal ligament injection; Anesthesia; Pain; Deciduous molars

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