Title
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Recent research progress on antibacterial modifications of conventional glass ionomer cement for dental restorations: a narrative review
1School of Stomatology, Lanzhou University, 730000 Lanzhou, Gansu, China
2Department of Stomatology, the 940th Hospital of Joint Logistic Support Force of the Chinese People’s Liberation Army, 730050 Lanzhou, Gansu, China
3The Affiliated Hospital of Southwest Jiaotong University & the Third People’s Hospital of Chengdu, 610031 Chengdu, Sichuan, China
DOI: 10.22514/jocpd.2026.002 Vol.50,Issue 1,January 2026 pp.11-26
Submitted: 10 February 2025 Accepted: 10 April 2025
Published: 03 January 2026
*Corresponding Author(s): Fuxiang Song E-mail: songfuxiang@lzu.edu.cn
*Corresponding Author(s): Bin Liu E-mail: liubkq@lzu.edu.cn
*Corresponding Author(s): Yanwei Yang E-mail: yangyanwei85@163.com
† These authors contributed equally.
Glass ionomer cement (GIC) has been widely used in the field of oral therapy because of its excellent properties. Good oral biocompatibility and easy clinical operation are important advantages of GIC. However, GIC still faces many challenges in its application as a repair material such as secondary caries and low mechanical properties. Recent studies have shown that conventional GIC is frequently insufficient for effective antibacterial protection. Therefore, many researchers have explored improving the antibacterial properties of GIC to prevent secondary caries by incorporating various materials with antibacterial properties into GIC. In this review, the recent research on GIC modified by antibacterial materials was systematically reviewed. The antibacterial mechanisms of various types of antibacterial materials were discussed in detail, and views on future research development were presented considering the current challenges in the field of GIC antibacterial modification.
Glass ionomer cement; Antibacterial; Modification; Narrative review
Qiushi Zhang,Yan Huang,Jianxue Li,Xinyu Yan,Ruijie Ma,Fuxiang Song,Bin Liu,Yanwei Yang. Recent research progress on antibacterial modifications of conventional glass ionomer cement for dental restorations: a narrative review. Journal of Clinical Pediatric Dentistry. 2026. 50(1);11-26.
[1] GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016; 388: 1545–1602.
[2] Guo T, Wang D, Gao SS. Incorporating nanosilver with glass ionomer cement—a literature review. Journal of Dentistry. 2024; 149: 105288.
[3] Avoaka-Boni MC, Djolé SX, Désiré Kaboré WA, D Gnagne-Koffi YN, E Koffi AF. The causes of failure and the longevity of direct coronal restorations: a survey among dental surgeons of the town of Abidjan, Côte d’Ivoire. Journal of Conservative Dentistry and Endodontics. 2019; 22: 270–274.
[4] Cheng XG, Wu HZ, Wang YR, Li YJ, Yu Q. Research and progress in etiology, prevention and treatment strategies of secondary caries. Chinese Journal of Stomatology. 2024; 59: 94–98. (In Chinese)
[5] Hosida TY, Delbem ACB, Morais LA, Moraes JCS, Duque C, Souza JAS, et al. Ion release, antimicrobial and physio-mechanical properties of glass ionomer cement containing micro or nanosized hexametaphosphate, and their effect on enamel demineralization. Clinical Oral Investigations. 2019; 23: 2345–2354.
[6] Gomes FS, Campos-Ferreira PV, Macedo RFC, Costa-Oliveira BE, Bauer J. Glass ionomer cement particles pre-reacted with chlorhexidine: physical/chemical properties and antimicrobial activity. Journal of the Mechanical Behavior of Biomedical Materials. 2024; 158: 106678.
[7] Meneses IHC, Sampaio GAM, Carvalho FG, Carlo HL, Münchow EA, Pithon MM, et al. In vivo biocompatibility, mechanical, and antibacterial properties of cements modified with propolis in different concentrations. European Journal of Dentistry. 2020; 14: 77–84.
[8] Vamsi K, Siddiqui F. Antimicrobial effect of an experimental glass lonomer cement against pathogens associated with deep carious lesions. The Journal of Contemporary Dental Practice. 2018; 19: 824–829.
[9] Yan H, Yang H, Li K, Yu J, Huang C. Effects of chlorhexidine-encapsulated mesoporous silica nanoparticles on the anti-biofilm and mechanical properties of glass ionomer cement. Molecules. 2017; 22: 1225.
[10] Cevallos González FM, Dos Santos Araújo EM, Lorenzetti Simionato MR, Kfouri Siriani L, Armas Vega ADC, Studart Medeiros I, et al. Effects of theobromine addition on chemical and mechanical properties of a conventional glass ionomer cement. Progress in Biomaterials. 2019; 8: 23–29.
[11] Porter GC, Tompkins GR, Schwass DR, Li KC, Waddell JN, Meledandri CJ. Anti-biofilm activity of silver nanoparticle-containing glass ionomer cements. Dental Materials. 2020; 36: 1096–1107.
[12] Guo T, Yang M, Wang D, Zheng J, Gao SS. Antibiofilm and mechanical properties of silver nanowire-modified glass ionomer cement. Journal of Dentistry. 2023; 135: 104569.
[13] Dashper SG, Catmull DV, Liu SW, Myroforidis H, Zalizniak I, Palamara JE, et al. Casein phosphopeptide-amorphous calcium phosphate reduces streptococcus mutans biofilm development on glass ionomer cement and disrupts established biofilms. PLOS ONE. 2016; 11: e0162322.
[14] Parcheta M, Sobiesiak M. Preparation and functionalization of polymers with antibacterial properties-review of the recent developments. Materials. 2023; 16: 4411.
[15] Imran M, Mallick R, Vadlamani R, Dhar A. Assessment of the antimicrobial efficacy and mechanical properties of glass ionomer cement (GIC) incorporating silver nanoparticles in varying concentrations for pediatric dental applications. Journal of Pharmacy and Bioallied Sciences. 2024; 16: S3689–S3691.
[16] Siqueira PC, Magalhães AP, Pires WC, Pereira FC, Silveira-Lacerda EP, Carrião MS, et al. Cytotoxicity of glass ionomer cements containing silver nanoparticles. Journal of Clinical and Experimental Dentistry. 2015; 7: e622–e627.
[17] Abed FM, Kotha SB, AlShukairi H, Almotawah FN, Alabdulaly RA, Mallineni SK. Effect of different concentrations of silver nanoparticles on the quality of the chemical bond of glass ionomer cement dentine in primary teeth. Frontiers in Bioengineering and Biotechnology. 2022; 10: 816652.
[18] Alshehri TD, Kotha SB, Abed FM, Barry MJ, AlAsmari A, Mallineni SK. Effect of the addition of varying concentrations of silver nanoparticles on the fluoride uptake and recharge of glass ionomer cement. Nanomaterials. 2022; 12: 1971.
[19] Park MV, Neigh AM, Vermeulen JP, de la Fonteyne LJ, Verharen HW, Briedé JJ, et al. The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles. Biomaterials. 2011; 32: 9810–9817.
[20] Aillón-García P, Parga-Landa B, Guillén-Grima F. Effectiveness of copper as a preventive tool in health care facilities. A systematic review. American Journal of Infection Control. 2023; 51: 1038–1048.
[21] Ma X, Zhou S, Xu X, Du Q. Copper-containing nanoparticles: mechanism of antimicrobial effect and application in dentistry—a narrative review. Frontiers in Surgery. 2022; 9: 905892.
[22] Aguilar-Perez D, Vargas-Coronado R, Cervantes-Uc JM, Rodriguez-Fuentes N, Aparicio C, Covarrubias C, et al. Antibacterial activity of a glass ionomer cement doped with copper nanoparticles. Dental Materials Journal. 2020; 39: 389–396.
[23] Ashour AA, Felemban MF, Felemban NH, Enan ET, Basha S, Hassan MM, et al. Comparison and advanced antimicrobial strategies of silver and copper nanodrug-loaded glass ionomer cement against dental caries microbes. Antibiotics. 2022; 11: 756.
[24] Pasha M, Muhammad N, Nayyer M, Bokhari JH, Ashraf H, Safi SZ, et al. Synthesis of an anti-cariogenic experimental dental composite containing novel drug-decorated copper particles. Materials Science & Engineering C, Materials for Biological Applications. 2020; 114: 111040.
[25] Hernández-Moreno D, Li L, Connolly M, Conde E, Fernández M, Schuster M, et al. Mechanisms underlying the enhancement of toxicity caused by the coincubation of zinc oxide and copper nanoparticles in a fish hepatoma cell line. Environmental Toxicology and Chemistry. 2016; 35: 2562–2570.
[26] Vega-Jiménez AL, González-Alva P, Rodríguez-Hernández AP, Vázquez-Olmos AR, Paz-Díaz B. Oxide nanoparticles based in magnesium as a potential dental tool to inhibit bacterial activity and promote osteoblast viability. Dental Materials Journal. 2024; 43: 11–19.
[27] Noori AJ, Kareem FA. The effect of magnesium oxide nanoparticles on the antibacterial and antibiofilm properties of glass-ionomer cement. Heliyon. 2019; 5: e02568.
[28] Naguib GH, Hosny KM, Hassan AH, Al Hazmi F, Al Dharrab A, Alkhalidi HM, et al. Zein based magnesium oxide nanoparticles: assessment of antimicrobial activity for dental implications. Pakistan Journal of Pharmaceutical Sciences. 2018; 31: 245–250.
[29] Naguib GH, Nassar HM, Hamed MT. Antimicrobial properties of dental cements modified with zein-coated magnesium oxide nanoparticles. Bioactive Materials. 2021; 8: 49–56.
[30] Mirhosseini F, Amiri M, Daneshkazemi A, Zandi H, Javadi ZS. Antimicrobial effect of different sizes of nano zinc oxide on oral microorganisms. Frontiers in Dentistry. 2019; 16: 105–112.
[31] Aydin Sevinç B, Hanley L. Antibacterial activity of dental composites containing zinc oxide nanoparticles. Journal of Biomedical Materials Research. 2010; 94: 22–31.
[32] Panahandeh N, Torabzadeh H, Aghaee M, Hasani E, Safa S. Effect of incorporation of zinc oxide nanoparticles on mechanical properties of conventional glass ionomer cements. Journal of Conservative Dentistry. 2018; 21: 130–135.
[33] Garcia PPNS, Cardia MFB, Francisconi RS, Dovigo LN, Spolidório DMP, de Souza Rastelli AN, et al. Antibacterial activity of glass ionomer cement modified by zinc oxide nanoparticles. Microscopy Research and Technique. 2017; 80: 456–461.
[34] Malekhoseini Z, Rezvani MB, Niakan M, Atai M, Bassir MM, Alizade HS, et al. Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement. Dental Research Journal. 2021; 18: 73.
[35] Veselova VO, Plyuta VA, Kostrov AN, Vtyurina DN, Abramov VO, Abramova AV, et al. Long-term antimicrobial performance of textiles coated with ZnO and TiO2 nanoparticles in a tropical climate. Journal of Functional Biomaterials. 2022; 13: 233.
[36] Kunrath MF, Farina G, Sturmer LBS, Teixeira ER. TiO2 nanotubes as an antibacterial nanotextured surface for dental implants: systematic review and meta-analysis. Dental Materials. 2024; 40: 907–920.
[37] Ramić B, Cvjetićanin M, Bajkin B, Drobac M, Milanović M, Rajnović D, et al. Physical and mechanical properties assessment of glass ionomer cements modified with TiO2 and Mg-doped hydroxyapatite nanoparticles. Journal of Applied Biomaterials & Functional Materials. 2024; 22: 22808000241282184.
[38] Mahendra TV, Rahul TS, Ramesh K, Pasupuleti S, Velagala SK, Mulakala V. Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study. European Oral Research. 2024; 58: 8–13.
[39] Araújo IJS, Ricardo MG, Gomes OP, Giovani PA, Puppin-Rontani J, Pecorari VA, et al. Titanium dioxide nanotubes added to glass ionomer cements affect S. mutans viability and mechanisms of virulence. Brazilian Oral Research. 2021; 35: e062.
[40] Hamid N, Telgi RL, Tirth A, Tandon V, Chandra S, Chaturvedi RK. Titanium dioxide nanoparticles and cetylpyridinium chloride enriched glass-ionomer restorative cement: a comparative study assessing compressive strength and antibacterial activity. Journal of Clinical Pediatric Dentistry. 2019; 43: 42–45.
[41] Wassel MO, Allam GG. Anti-Bacterial effect, fluoride release, and compressive strength of a glass ionomer containing silver and titanium nanoparticles. Indian Journal of Dental Research. 2022; 33: 75–79.
[42] das Neves MV, da Silva TM, Lima Ede O, da Cunha EV, Oliveira Ede J. Isoflavone formononetin from red propolis acts as a fungicide against Candida sp. Brazilian Journal of Microbiology. 2016; 47: 159–166.
[43] Meto A, Colombari B, Meto A, Boaretto G, Pinetti D, Marchetti L, et al. Propolis affects pseudomonas aeruginosa growth, biofilm formation, eDNA release and phenazine production: potential involvement of polyphenols. Microorganisms. 2020; 8: 243.
[44] Silici S, Koç NA, Ayangil D, Cankaya S. Antifungal activities of propolis collected by different races of honeybees against yeasts isolated from patients with superficial mycoses. Journal of Pharmacological Sciences. 2005; 99: 39–44.
[45] Neelima B, Reddy JS, Singh PT, Suhasini K, Hemachandrika I, Hasanuddin S. Comparative evaluation of antimicrobial efficacy of glass ionomer cement added with propolis, chitosan, and chlorhexidine against Streptococcus mutans and Lactobacillus acidophilus: an in vitro study. Journal of Indian Society of Pedodontics and Preventive Dentistry. 2020; 38: 367–373.
[46] de Morais Sampaio GA, Lacerda-Santos R, Cavalcanti YW, Vieira GHA, Nonaka CFW, Alves PM. Antimicrobial properties, mechanics, and fluoride release of ionomeric cements modified by red propolis. The Angle Orthodontist. 2021; 91: 522–527.
[47] Elmenshawy MZ, El-Haliem HA, Mowafy AM, Hamama HH. Effect of ethanolic extract of propolis on antibacterial and microshear bond strength of glass-ionomer restorations to dentin. Heliyon. 2023; 10: e23710.
[48] Tardugno R, Pellati F, Iseppi R, Bondi M, Bruzzesi G, Benvenuti S. Phytochemical composition and in vitro screening of the antimicrobial activity of essential oils on oral pathogenic bacteria. Natural Product Research. 2018; 32: 544–551.
[49] Sakkas H, Papadopoulou C. Antimicrobial activity of basil, oregano, and thyme essential oils. Journal of Microbiology and Biotechnology. 2017; 27: 429–438.
[50] Nunes JMFF, Farias IAP, Vieira CA, Ribeiro TM, Sampaio FC, Menezes VA. Antimicrobial activity and toxicity of glass ionomer cement containing an essential oil. Brazilian Journal of Medical and Biological Research. 2020; 53: e9468.
[51] Sherief DI, Fathi MS, Abou El Fadl RK. Antimicrobial properties, compressive strength and fluoride release capacity of essential oil-modified glass ionomer cements—an in vitro study. Clinical Oral Investigations. 2021; 25: 1879–1888.
[52] Li J, Xie X, Wang Y, Yin W, Antoun JS, Farella M, et al. Long-term remineralizing effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on early caries lesions in vivo: a systematic review. Journal of Dentistry. 2014; 42: 769–777.
[53] Zhao IS, Mei ML, Burrow MF, Lo EC, Chu CH. Prevention of secondary caries using silver diamine fluoride treatment and casein phosphopeptide-amorphous calcium phosphate modified glass-ionomer cement. Journal of Dentistry. 2017; 57: 38–44.
[54] Mao B, Xie Y, Yang H, Yu C, Ma P, You Z, et al. Casein phosphopeptide-amorphous calcium phosphate modified glass ionomer cement attenuates demineralization and modulates biofilm composition in dental caries. Dental Materials Journal. 2021; 40: 84–93.
[55] Kirthika N, Vidhya S, Sujatha V, Mahalaxmi S, Senthil Kumar R. Comparative evaluation of compressive and flexural strength, fluoride release and bacterial adhesion of GIC modified with CPP-ACP, bioactive glass, chitosan and MDPB. Journal of Dental Research, Dental Clinics, Dental Prospects. 2021; 15: 16–21.
[56] Amaechi BT, Mathews SM, Mensinkai PK. Effect of theobromine-containing toothpaste on dentin tubule occlusion in situ. Clinical Oral Investigations. 2015; 19: 109–116.
[57] Ghorbani A, Esmaeilizadeh M. Pharmacological properties of Salvia officinalis and its components. Journal of Traditional and Complementary Medicine. 2017; 7: 433–440.
[58] Kermanshah H, Kamangar SS, Arami S, Kamalinegad M, Karimi M, Mirsalehian A, et al. The effect of hydro alcoholic extract of seven plants on cariogenic bacteria—an in vitro evaluation. Oral Health and Dental Management. 2014; 13: 395–401.
[59] Beheshti-Rouy M, Azarsina M, Rezaie-Soufi L, Alikhani MY, Roshanaie G, Komaki S. The antibacterial effect of sage extract (Salvia officinalis) mouthwash against Streptococcus mutans in dental plaque: a randomized clinical trial. Iranian Journal of Microbiology. 2015; 7: 173–177.
[60] Shahriari S, Barekatain M, Shahtalebi MA, Farhad SZ. Evaluation of preventive antibacterial properties of a glass-ionomer cement containing purified powder of Salvia officinalis: an in vitro study. International Journal of Preventive Medicine. 2019; 10: 110.
[61] Garcia LSG, Delbem ACB, Pessan JP, Dos Passos Silva M, Neto FNS, Gorup LF, et al. Anticaries effect of toothpaste with nano-sized sodium hexametaphosphate. Clinical Oral Investigations. 2019; 23: 3535–3542.
[62] Lee C, Wei X, Kysar JW, Hone J. Measurement of the elastic properties and intrinsic strength of monolayer graphene. Science. 2008; 321: 385–388.
[63] Al-Jumaili A, Alancherry S, Bazaka K, Jacob MV. Review on the antimicrobial properties of carbon nanostructures. Materials. 2017; 10: 1066.
[64] Sun L, Yan Z, Duan Y, Zhang J, Liu B. Improvement of the mechanical, tribological and antibacterial properties of glass ionomer cements by fluorinated graphene. Dental Materials. 2018; 34: e115–e127.
[65] Liu R, Wang E, Guo Y, Zhou Q, Zheng Y, Zhai J, et al. Enhanced antibacterial properties and promoted cell proliferation in glass ionomer cement by modified with fluorinated graphene-doped. Journal of Applied Biomaterials & Functional Materials. 2021; 19: 22808000211037487.
[66] Mohammadi Z, Jafarzadeh H, Shalavi S. Antimicrobial efficacy of chlorhexidine as a root canal irrigant: a literature review. Journal of Oral Science. 2014; 56: 99–103.
[67] da Silva MER, Danelon M, Santos Souza JA, Silva DF, Pereira JA, Pedrini D, et al. Incorporation of chlorhexidine and nano-sized sodium trimetaphosphate into a glass-ionomer cement: effect on mechanical and microbiological properties and inhibition of enamel demineralization. Journal of Dentistry. 2019; 84: 81–88.
[68] Ratnayake J, Veerasamy A, Ahmed H, Coburn D, Loch C, Gray AR, et al. Clinical and microbiological evaluation of a chlorhexidine-modified glass ionomer cement (GIC-CHX) restoration placed using the atraumatic restorative treatment (ART) technique. Materials. 2022; 15: 5044.
[69] Walsh T, Oliveira-Neto JM, Moore D. Chlorhexidine treatment for the prevention of dental caries in children and adolescents. Cochrane Database of Systematic Reviews. 2015; 2015: CD008457.
[70] De Morais DC, Jackson JK, Kong JH, Ghaffari S, Palma-Dibb RG, Carvalho RM, et al. Characterization of polymethylmethacrylate microspheres loaded with silver and doxycycline for dental materials applications. Dental Materials. 2022; 38: 946–959.
[71] Enan ET, Ashour AA, Basha S, Felemban NH, Gad El-Rab SMF. Antimicrobial activity of biosynthesized silver nanoparticles, amoxicillin, and glass-ionomer cement against Streptococcus mutans and Staphylococcus aureus. Nanotechnology. 2021; 32: 215101.
[72] Chen J, Zhao Q, Peng J, Yang X, Yu D, Zhao W. Antibacterial and mechanical properties of reduced graphene-silver nanoparticle nanocomposite modified glass ionomer cements. Journal of Dentistry. 2020; 96: 103332.
[73] Siddiqui A, Gul A, Khan H, Anjum F, Hussain T. Bio-inspired synthesis of silver nanoparticles using Salsola imbricate and its application as antibacterial additive in glass ionomer cement. Nanotechnology. 2024; 35: 355101.
[74] Ibrahim MA, Meera Priyadarshini B, Neo J, Fawzy AS. Characterization of chitosan/TiO2 nano-powder modified glass-ionomer cement for restorative dental applications. Journal of Esthetic and Restorative Dentistry. 2017; 29: 146–156.
[75] Sun J, Xu Y, Zhu B, Gao G, Ren J, Wang H, et al. Synergistic effects of titanium dioxide and cellulose on the properties of glassionomer cement. Dental Materials Journal. 2019; 38: 41–51.
[76] Bellis CA, Nobbs AH, O’Sullivan DJ, Holder JA, Barbour ME. Glass ionomer cements functionalised with a concentrated paste of chlorhexidine hexametaphosphate provides dose-dependent chlorhexidine release over at least 14 months. Journal of Dentistry. 2016; 45: 53–58.
[77] Hosida TY, Pessan JP, Cavazana TP, Sampaio C, de Morais LA, Monteiro DR, et al. Effects of sodium hexametaphosphate and fluoride on the pH and inorganic components of streptococcus mutans and candida albicans biofilm after sucrose exposure. Antibiotics. 2022; 11: 1044.
[78] Joshi RS, Gokhale NS, Hugar SM, Soneta SP, Badakar CM, Patil VH. Comparative evaluation of antibacterial efficacy of conventional glass-ionomer cement and bulk-fill alkasite material when combined with doxycycline and double antibiotic paste containing ciprofloxacin and metronidazole against Streptococcus mutans and Lactobacillus spp.: an in vitro study. Journal of Indian Society of Pedodontics and Preventive Dentistry. 2020; 38: 361–366.
[79] Ashour AA, Basha S, Felemban NH, Enan ET, Alyamani AA, Gad El-Rab SMF. Antimicrobial efficacy of glass ionomer cement in incorporation with biogenic zingiber officinale capped silver-nanobiotic, chlorhexidine diacetate and lyophilized miswak. Molecules. 2022; 27: 528.
[80] Kurt A, Tüzüner T, Baygın Ö. Antibacterial characteristics of glass ionomer cements containing antibacterial agents: an in vitro study. European Archives of Paediatric Dentistry. 2021; 22: 49–56.
[81] Manisha S, Shetty SS, Mehta V, Sa R, Meto A. A comprehensive evaluation of zirconia-reinforced glass ionomer cement’s effectiveness in dental caries: a systematic review and network meta-analysis. Dentistry Journal. 2023; 11: 211.
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