A case of orthodontic treatment with early tooth extraction and a functional orthodontic appliance in a patient with familial Mediterranean fever

Background: Familial Mediterranean fever (FMF) is a systemic autoinflammatory disease characterized by recurrent attacks of fever, abdominal or chest pain, and joint pain that resolve spontaneously within a short period. There have been few reports of orthodontic treatment in patients with FMF. Case: The patient was a girl aged 10 years and 7 months who had been diagnosed with FMF at 1 year old. To improve severe maxillary and mandibular crowding and retruded mandible, orthodontic treatment was performed with early extraction of the bilateral maxillary and mandibular first premolars and the use of a functional orthodontic appliance, which helped improve the skeletal problems characteristic to patients with FMF. No notable attacks were reported during the orthodontic treatment period. Conclusion: This case can be a model case of orthodontic treatment for patients with FMF starting from childhood.

Familial Mediterranean fever; Autoinflammatory; Orthodontic treatment; Early extraction; Functional appliances

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