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Monostotic Langerhans’ Cell Histiocytosis in a Child with Central Diabetes Insipidus

  • Costa Studart Soares E1,*,
  • Quidute ARP1
  • Gurgel Costa FW1
  • Costa Gurgel MH1
  • Negreiros Nunes Alves AP 1
  • Sá Roriz Fonteles C1

1Federal University of Ceará, Brazil, Coordenação do Curso de Odontologia da Universidade Federal do Ceará Campus Sobral

2 Av. Comandante Maurocélio Rocha Pontes, s/n.º

3, Derby

4 CEP 62.041-040, Sobral-Ce, Brazil.

DOI: 10.17796/jcpd.36.4.aq167251703n767u Vol.36,Issue 4,July 2012 pp.377-381

Published: 01 July 2012

*Corresponding Author(s): Costa Studart Soares E E-mail: fwildson@yahoo.com.br

Abstract

Langerhans’ cell histiocytosis (LCH) comprises a rare group of reticuloendothelial system disorders that can produce focal or systemic manifestations. Diabetes insipidus is considered to be an important indicator of serious underlying diseases in children, including LCH. We report the case of a young patient with monostotic LCH confined to the mandibular ramus, who was diagnosed with the disease after presenting symptoms of central diabetes insipidus and was satisfactorily treated with multi-agent chemotherapy. Additionally, we discuss the clinical, radiographic, histological and immunohistochemical findings, as well as the multidisciplinary approach of this important disease, which should receive attention by dental practitioners, especially when it occurs in children.

Keywords

Langerhans cell histiocytosis; mandible; children; central diabetes insipidus; chemotherapy.

Cite and Share

Costa Studart Soares E,Quidute ARP,Gurgel Costa FW,Costa Gurgel MH,Negreiros Nunes Alves AP ,Sá Roriz Fonteles C. Monostotic Langerhans’ Cell Histiocytosis in a Child with Central Diabetes Insipidus. Journal of Clinical Pediatric Dentistry. 2012. 36(4);377-381.

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