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Idiopathic Ulcers as an Oral Manifestation in Pediatric Patients with AIDS: Multidisciplinary Management

  • Martinez-Sandoval B1
  • Ceballos-Hernández H2
  • Téllez-Rodríguez J2
  • Xochihua-Díaz L3
  • Durán-Ibarra G4
  • Pozos-Guillen AJ4,*,

1Pediatric Dentistry Service, Instituto Nacional de Pediatría

2 Pediatric Dentistry Postgraduate Program, Facultad de Estomatología, Universidad Autónoma de San Luis Potosí, México

3Pediatric Dentistry Service, Instituto Nacional de Pediatría, México, D.F., México

4Pediatric Infectious Diseases Service, Instituto Nacional de Pediatría, México

5Pediatric Dentistry Postgraduate Program, Facultad de Estomatología, Universidad Autónoma de San Luis Potosí, México

DOI: 10.17796/jcpd.37.1.5328h67527165u88 Vol.37,Issue 1,January 2013 pp.65-70

Published: 01 January 2013

*Corresponding Author(s): Pozos-Guillen AJ E-mail: apozos@uaslp.mx

Abstract

HIV infection is a major global health problem affecting developing and developed countries alike. HIV infection is associated with multiple oral lesions, some of which are of value in diagnosing the disease. The aim of this report is to describe the clinical manifestations and their multidisciplinary management, in a 6- year-old girl with AIDS. The findings of this case report indicate that, it is essential to be familiar with the early oral manifestations of AIDS in order to understand the patient's dental health needs, apply preventive methods, control caries, and understand the value of oral lesions as diagnostic markers of disease progression in children with HIV infection. A multidisciplinary management is fundamental.

Keywords

HIV/AIDS, pediatric patients, oral manifestations, atypical ulcers

Cite and Share

Martinez-Sandoval B,Ceballos-Hernández H,Téllez-Rodríguez J,Xochihua-Díaz L,Durán-Ibarra G,Pozos-Guillen AJ. Idiopathic Ulcers as an Oral Manifestation in Pediatric Patients with AIDS: Multidisciplinary Management. Journal of Clinical Pediatric Dentistry. 2013. 37(1);65-70.

References

1. Mittal M. AIDS in children: epidemiology, clinical course, oral mani-festations and management. J Clin Pediatr Dent, 34: 95–102, 2009.

2. ONUSIDA/09.36S / JC1700S (versión española, diciembre de 2009). Situación  de  la  Epidemia  de  SIDA,  2009.  Available  from: http://www.censida.salud.gob.mx/descargas/cifras_mundo/situacion_e pidemia2009.pdf

3. Centro Nacional para la Prevención y Control del VIH/SIDA. México, D. F.:  Registro  Nacional  de  Casos  de  SIDA.  Casos  acumulados  de SIDA  por  edad  y  sexo.  Available  from:  http://www.censida.salud. gob.mx/descargas/2010/15nov2010/casos_grupoedadysexo.pdf

4. Chávez PA, Álvarez PA, Wu HE, Peña DA, Vizueta RE. Evolución de la transmisión vertical de la infección por virus de inmunodeficiencia humana en Chile. Rev Chil Infect, 24: 368–37, 2007.

5. Jourdain G, Mary JY, Coeur SL, et al. Risk factors for in utero or intra-partum  mother-to-child  transmission  of  human  immunodeficiency virus type 1 in Thailand. J Infect Dis, 196: 1629–36, 2007.

6. Martínez RH, Morales QC, Torres GF. Manifestaciones mucocutáneas en niños nacidos de madres VIH seropositivas. Rev Mex Pediatr, 2000; 67: 214–219, 2000.

7. Aguirre  UJ,  Echevarría  GM.  Síndrome  de  inmunodeficiencia  adqui-rida:  Manifestaciones  en  la  cavidad  bucal.  Med  Oral  Patol  Oral  Cir Bucal, 9: 148–57, 2004.

8. Itin PH, Lautenschlager S, Flückiger R, Rufli T. Oral manifestations in HIV-infected  patients:  Diagnosis  and  management.  J  Am  Acad Dermatol, 29: 749–60, 1993.

9. Khatibi M, Moshari AA, Jahromi ZM, Ramezankhani A. Prevalence of oral mucosal lesions and related factors in 200 HIV(+) /AIDS Iranian patients.  J  Oral  Pathol  Med,  doi:10.1111/j.1600-0714.2011.01013.x, 2011.

10. Cerqueira  DF,  Portela  MB,  Pomarico  L,  de  Araújo  Soares  RM,  de Souza IP, Castro GF. Oral Candida colonization and its relation with predisposing factors in HIV-infected children and their uninfected sib-lings in Brazil: The era of highly active antiretroviral therapy. J Oral Pathol Med, 39: 188–94, 2010.

11. Leao JC, Ribeiro CM, Carvalho AA, Frezzini C, Porter S. Oral com-plications of HIV disease. Clinics (Sao Paulo), 64: 459–70, 2009.

12. Martínez RH. Prevención y tratamiento de la desnutrición en niños con VIH. Rev Mex Pediatr, 69: 155–163, 2002.

13. Bosco VL, Birman EG. Oral manifestations in children with AIDS and in controls. Pesqui Odontol Bras, 16: 7–11, 2002.

14. Tirwomwe JF, Rwenyonyi CM, Muwazi LM, Besigye B, Mboli F. Oral manifestations  of  HIV/AIDS  in  clients  attending  TASO  clinics  in Uganda. Clin Oral Investig, 11: 289–92, 2007.

15. Uriarte-Duque J, Hernández-Riverab G. Treatment of non-Hodgkin’s lymphoma  associated  with  acquired  immnodeficiency  syndrome (AIDS)  at  the  Instituto  Nacional  de  Ciencias  Médicas  y  Nutrición Salvador Zubirán, Gac Med Mex, 142: 99–102, 2006.

16. Ramírez Z, Román A, Rugeles MT, Carlos Aguirre C. Situaciones clí-nicas  importantes  en  niños  infectados  por  el  Virus  de  la Inmunodeficiencia Humana (VIH). IATREIA, 19: 172–88, 2006.

17. Scully C, McCarthy G. Management of oral health in persons with HIV infection. Oral Surg Oral Med Oral Pathol, 73: 215–25, 1992.

18. Massarente DB, Domaneschi C, Marques HH, Andrade SB, Goursand D, Antunes JL. Oral health-related quality of life of paediatric patients with AIDS. BMC Oral Health, 11: 2–7, 2011.

19. Cauda R, Facconelli E, Tumbarello M. Role of protease inhibitors in prevention recurrent oral candidiasis in patients with HIV infection: A prospective  case-control  study.  J  Acquir  Immunodefic  Syndr,  21: 20–25, 1999.

20. Eyeson  JD,  Tenant-Flowers  M,  Cooper  DJ,  Johnson  NW, Warnakulasuriya KA. Oral manifestations of an HIV positive cohort in the  era  of  highly  active  anti-retroviral  therapy  (HAART)  in  South London. J Oral Pathol Med, 31: 169–74, 2002.

21. Frezzini  C,  Leao  JC,  Porter  S.  Current  trends  of  HIV  disease  of  the mouth. J Oral Pathol Med, 34: 513–31 2005.

22. Gaitán-Cepeda LA, Domínguez-Sánchez A, Pavía-Ruz N, et al. Oral lesions  in  HIV+/AIDS  adolescents  perinatally  infected  undergoing HAART. Med Oral Patol Oral Cir Bucal, 15: e545–50, 2010.

23. Nicolatou-Galitis  O,  Velegraki  A,  Paikos  S,  Economopoulou  P, Stefaniotis T, Papanikolaou IS, Kordossis T. Effect of PI-HAART on the prevalence of oral lesions in HIV-1 infected patients. A Greek study. Oral Dis, 10: 145–50, 2004.

24. Ortega  KL,  Vale  DA,  Magalhães  MH.  Impact  of  PI  and  NNRTI HAART-based  therapy  on  oral  lesions  of  Brazilian  HIV-infected patients. J Oral Pathol Med, 38: 489–94, 2009. 

25. Tappuni AR,  Fleming  GJ. The  effect  of  antiretroviral  therapy  on  the prevalence of oral manifestations in HIV-infected patients: A UK study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 92: 623–8, 2001.

26. dos Santos Pinheiro R, França TT, Ribeiro CM, Leão JC, de Souza IP, Castro  GF.  Oral  manifestations  in  human  immunodeficiency  virus infected  children  in  highly  active  antiretroviral  therapy  era.  J  Oral Pathol Med, 38: 613–22, 2009. 

27. Kozinetz CA, Carter AB, Simon C, et al. Oral manifestations of pedi-atric  vertical  HIV  infection.  AIDS  Patient  Care  STDS,  14:  89–94, 2000. 

28. Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus  infection.  HIV  Outpatient  Study  Investigators.  N  Engl  J  Med, 338: 853–60, 1998.

29. Ranganathan K, Geethalakshmi E, Krishna Mohan Rao U, Vidya KM, Kumarasamy N, Solomon S. Orofacial and systemic manifestations in 212 paediatric HIV patients from Chennai, South India. Int J Paediatr Dent, 20: 276–82, 2010.

30. Ramírez-Amador V, Esquivel-Pedraza L, Irigoyen-Camacho E, Anaya-Saavedra G, González-Ramírez I. Association of oral lesions with HIV serological status. Salud Publica Mex, 44: 87–91, 2002.

31. Ramirez-Amador V, Esquivel-Pedraza L, Sierra-Madero J, Ponce-de-Leon  S,  Ponce-de-Leon  S.  Oral  manifestations  of  HIV  infection  by gender and transmission category in Mexico City. J Oral Pathol Med, 27: 135–40, 1998.

32. Eldridge K, Gallagher JE. Dental caries prevalence and dental health behaviour  in  HIV  infected  children.  Int  J  Paediatr  Dent,  10:  19–26, 2000.

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