Article Data

  • Views 687
  • Dowloads 224

Original Research

Open Access

In Vivo Evaluation of Lesion Sterilization and Tissue Repair in Primary Teeth Pulp Therapy Using Two Antibiotic Drug Combinations

  • Jaya AR1
  • Praveen P2,*,
  • Anantharaj A2
  • Venkataraghavan K3
  • Prathibha Rani S2

1Department of Pedodontics, Rajarajeshwari Dental College, Bangalore

2Department of Pediatric and Preventive Dentistry, D.A.P.M.R.V Dental College, Bangalore

3Department of Pediatric and Preventive Dentistry, College of Dental Sciences & Research, Ahmedabad, Gujrat

DOI: 10.17796/jcpd.37.2.e5131jp6m1w33v66 Vol.37,Issue 2,March 2013 pp.189-192

Published: 01 March 2013

*Corresponding Author(s): Praveen P E-mail: drppraveen@gmail.com

Abstract

Aim : The purpose of this study is to evaluate and compare the clinical and radiographic effectiveness of Ciprofloxacin, Minocycline, Metronidazole combination with Ciprofloxacin, Minocycline and Tinidazole combination when used for Lesion Sterilization and Tissue Repair in primary teeth. Method: 25 healthy children, visiting Dept. of Pediatric & Preventive Dentistry, D.A.P.M.R.V.Dental College, Bangalore, India, aged between 6 - 9 years who were having 30 infected primary teeth are selected and divided into 2 groups. In Group A, a mixture of 3mix-MP Ciprofloxacin, Metronidazole and Minocycline was placed on the floor of the pulp chamber covering the root canal orifices. In Group B a mixture of Ciprofloxacin, Tinidazole and Minocycline was placed as a layer on the floor of the pulp chamber. The procedure was completed in a single visit. Post operative clinical evaluation was done after 1,6,12 and 24 months. Postoperative radiographic evaluation was done at 6,12 and 24 months. Results: No statistically significant difference is observed between both the groups and a combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs can be used on teeth pulpally involved with physiologic root resorption. Conclusion: After a 24 Month follow up, we can conclude that primary teeth with the periradicular lesions, can be conserved by using combination of Ciprofloxacin, Minocycline and Tinidazole antibacterial drugs.

Keywords

Lesion Sterilization and Tissue repair, Primary tooth, pulp therapy, Antibiotics, Ciprofloxacin, Minocycline, Tinidazole

Cite and Share

Jaya AR,Praveen P,Anantharaj A,Venkataraghavan K,Prathibha Rani S. In Vivo Evaluation of Lesion Sterilization and Tissue Repair in Primary Teeth Pulp Therapy Using Two Antibiotic Drug Combinations. Journal of Clinical Pediatric Dentistry. 2013. 37(2);189-192.

References

1. Camp JH Pediatric Endodontic Treatment. In Cohen S. Burns RC, eds. Pathways of the pulp. 6th edn. St Louis MO. USA Mosby. 633-671: 1994.

2. Finn SB. Clinical Pedodontics, 4th ed. Philadelphia: W.B. Saunders Company; 201-219:1995.

3. Guideline on pulp therapy of primary and immature permanent teeth. American Academy of Pediatric Dentistry. Revised, Ref.No.3, 33(6), 194- 201: 2009.

4. Prabhakar.AR, Sridevi.E, Raju OS, Satish.V. Endodontic Treatment of Primary teeth using combinatio of antibacterial drugs. J Indian Soc Pedod Prevent Dent: Suppl: 26: S5-S10, 2008

5. Cruz EV, Kota K, Huque J, Iwaku M, Hoshino E. Penetration of propylene glycol into dentine. Int Endod Journal: 35: 330-336: 2002.

6. Alam T, Nakazawa F, Nakajo K, Umetsu H, Hoshino E. Susceptibility of Enterococcus Faecalis to a combinaion of Antibacterial drugs (3mix) invitro. J Oral Biosci : 47(4): 315-320: 2005.

7. David HW. Treatment of metronidazole resistant trichomonas vaginalis with tinidazole: case reports of three patients. Sexually Transmitted Diseases. 31 (6): 343-345: 2004.

8. Abott PV, Hume Wr, Pearman JW: Antibiotics and Endodontics. 35 (10): 50- 60: 1990.

9. Shafer WG, Hine MK, Levy BM, Tomich CE: A textbook of ral Pathology, W. B Saunders Company: 4th Edition.: 669, 1997.

10. O’Riordan MW, Coll J. Pulpectomy procedure for deciduous teeh with severe Pulpal necrosis. J Am Dent Assoc: 99: 480-482: 1979.

11. Takushige T, Cruz Ev, Moral A, Hoshino E. Endodontic Treatment of primary teeth using combination of antibacterial drugs. Int Endod J: 37: 132- 138: 2004.

12. Thomas PA, Bhat KS, Kotian KM. Antibacterial Properties of Dilute Formoacresol and Eugenol and Propylene Glycol. Oral Surg: 49: 166-170: 1980.

13. Rocha MJ, Cardoso M, Endodontic treatment of traumatized primary teeth – Part2. Dent. Traumatol: 20(6) : 314-326: 2004.

14. Hoshino E, Asgor MA, Yagi M, Garcia MCG, Cruz EV, Oyanagi H, Kota K. Oral Health program using LSTR 3 Mix- MP NIET Therapy: Pulp Cell Behaviour: Pulp Therapy and Endod: 1786: 2006.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

PubMed (MEDLINE) PubMed comprises more than 35 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Scopus: CiteScore 2.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Submission Turnaround Time

Conferences

Top